DOI . ORG {}

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• Science
• Education
• Movies

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Custom-built

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🌌 Gigantic Traffic: 2M - 5M visitors per month


Based on our best estimate, this website will receive around 4,145,289 visitors per month in the current month.

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How Does Doi.org Make Money? {💸}

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Keywords {🔍}

dicer, cells, figure, expression, letip, sirna, cancer, hypoxia, crc, qpcr, hct, tumor, compared, mirna, shrna, levels, transfected, mrna, luciferase, reverse, cst, mimic, hypoxic, akt, cell, forward, western, shown, promoter, gapdh, emt, hypoxiainduced, metastasis, protein, signaling, site, binding, control, role, data, blotting, activity, normoxia, results, zhang, performed, internal, incubated, test, overexpression,

Topics {✒️}

7i-5p-p110α-akt-mtor signaling axis nur77-β-catenin feed-forward loop oncogenic pi3k/akt/mtorc1 signaling stabilizing hypoxia-inducible factor-1α heat-induced antigen retrieval pi3k/akt signaling pathway downstream p110α/akt/mtorc1 play orphan receptor tr3 hypoxia-inducible factor-1α hypoxia-inducible factor 1α small-cell lung carcinoma enhance β-catenin signaling intra-tumoral oxygen level methods cell lines pi3k/akt/mtor pathway discussion hypoxia nur77-regulated p110α/akt activation unique nuclear receptor hypoxia-induced nur77 expression specific stem-loop primers activating tgf-β signalling m-mlv reverse transcriptase representative images web-based tool survexpress renilla luciferase-expressing plasmid nuclear receptor nur77 kaplan-meier survival curves p110α/akt/mtor pathway pi3k/akt signaling high-sensitivity chip kit pgl3-dicer-prom plasmid anti-mouse secondary antibodies technology commission grant kaplan-meier plot showed nur77/dicer/p110α axis hypoxia activated p110α/akt induce nur77∆dbd interaction serial spheroid formation significant tumor-promoting activities regulate p110α/p-akt p110α mrna half-life putative p63-binding sites nur77-driven crc growth pgl3-dicer-promoter plasmid dicer-promoter reporter assays strongly develop secondary sphere-forming ability 7i-5p binding site sphere formation assays 7i-5p mimic compared

Questions {❓}

• Micro-RNAs as potential new molecular biomarkers in oncology: have they reached relevance for the clinical imaging sciences?

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