DOI . ORG {
}
Title[redir]:
Gemcitabine and XCT790, an ERRΞ± inverse agonist, display a synergistic anticancer effect in pancreatic cancer
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Keywords {π}
gemcitabine, xct, cell, cells, errΞ±, cancer, treatment, combination, effect, pancreatic, figure, synergistic, group, cycle, analysis, cellular, andor, results, resistance, minipdx, mekerk, synergism, activity, anticancer, emt, pathway, inhibition, mice, shanghai, tumor, assay, apoptosis, liu, study, apoptotic, growth, hours, data, medicine, drug, synergistically, inverse, agonist, yang, zheng, viability, assays, xenograft, models, therapy,
Topics {βοΈ}
gemcitabine-erlotinib versus gemcitabine-erlotinib-capecitabine estrogen-related receptor alpha mini patient-derived xenografts mini-pdx capsules-bearing mice g0/g1 retardation cdc25c/cdk1/cyclinb1 pathway erk/mapk signalling pathway mek/erk signal path micro-plate reading device mek/erk signaling pathway steponeplus real-time thermocycle vivo drug-response assay g0/g1 phase mek/erk pathway proteins mek/erk pathway plays patient-derived xenograft cellular cycle arrest cell cycle arrest uplifted long-period results cellular cycle assay programmed cell death cellular cycle-related sera-reduced dmem medium cellular cycle analysis cellular cycle arrested cell cycle distribution cell viability assays estrogen-related receptors pancreatic ductal adenocarcinoma apoptotic activity-related markers flow cell technique cell signaling technology mek/erk pathway western blot analysis mini-pdx assay xct790 dramatically inhibited international journal cell commun signal authors contributed equally castration-resistant growth xct790 synergistically suppress annu rev physiol xct790 synergistically decreased nat rev cancer gemcitabine-based chemical therapy xct790 potently inhibited remarkably reduced compared entire lineage cells guided chemotherapy based febs open bio
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