
DOI . ORG {
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Title[redir]:
Aryl Hydrocarbon Receptor Activation Inhibits In Vitro Differentiation of Human Monocytes and Langerhans Dendritic Cells1 | The Journal of Immunology | American Association of Immunologists
Description:
Abstract. The transcription factor aryl hydrocarbon receptor (AhR) represents a promising therapeutic target in allergy and autoimmunity. AhR signaling ind
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Keywords {🔍}
cells, ahr, vaf, cell, differentiation, fig, expression, cultures, lcs, activation, monocyte, monocytes, progenitor, blood, human, generation, presence, cda, receptor, generated, granulocytes, monocytic, analyzed, signaling, levels, induction, absence, hydrocarbon, dcs, shown, maturation, aryl, effect, ngml, vitro, analysis, ligands, tgfβ, dendritic, inhibition, cultured, experiments, gfp, open, gene, myeloid, expansion, control, days, inhibited,
Topics {✒️}
real-time rt-pcr analysis tnf-α/nf-κb signaling impairment tnf-α/nf-κb signaling real-time rt-pcr tnf-α-induced nfκb activation basic helix-loop-helix/ transforming growth factor-β1 g-csf-dependent granulocyte differentiation privacy policy transforming growth factor-β block nf-κb p65 healthy full-term deliveries tgf-β1-dependent lc cultures empty vector pbmn-ires-gfp share functional characteristics granulocyte colony-stimulating factor fitc-conjugated mabs specific serum-free conditions allophycocyanin-conjugated mabs specific langerhans-type dendritic cells potent anti-inflammatory activity pe-conjugated mabs specific tgf-β1 costimulation induces anti-cd40-induced activation open biosystems mimic tgf-β1 signaling lc-type dendritic cells cd14+cd11bdim/neg cells boosting il-17-producing helper lentiviral gipz-short-hairpin human monocyte-derived dcs retroviral construct pbmn-pu lineage-determining transcriptional processes cis-regulatory dna elements tgf-β1-dependent manner specific anti-proliferative effect m-csf/il-6-supplemented cultures monocyte-specific differentiation conditions human cord blood cell-dependent allergic asthma ah-receptor cdna reveals monocyte-derived dc generation monocyte/dc subset differentiation monocyte/dc lineage commitment 8 tetrachlorodibenzo-p-dioxin main modulatory effect generate monocyte-derived dcs m-csf-dependent monocyte ahr nuclear translocator mediating agonist-induced activation
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name:Aryl Hydrocarbon Receptor Activation Inhibits In Vitro Differentiation of Human Monocytes and Langerhans Dendritic Cells1
datePublished:2009-07-01
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type:PublicationIssue
issueNumber:1
datePublished:2009-07-01
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type:Periodical
name:The Journal of Immunology
issn:
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url:https://dx.doi.org/10.4049/jimmunol.0802997
inLanguage:en
copyrightHolder:
copyrightYear:2025
publisher:
author:
name:Platzer, Barbara
affiliation:* Division of Gastroenterology and Nutrition, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115;
type:Person
name:Richter, Susanne
affiliation:† Institute of Immunology, Center of Physiology, Pathophysiology and Immunology, Medical University Vienna, Vienna, Austria; and
type:Person
name:Kneidinger, Doris
affiliation:† Institute of Immunology, Center of Physiology, Pathophysiology and Immunology, Medical University Vienna, Vienna, Austria; and
type:Person
name:Waltenberger, Darina
affiliation:† Institute of Immunology, Center of Physiology, Pathophysiology and Immunology, Medical University Vienna, Vienna, Austria; and
type:Person
name:Woisetschläger, Maximilian
affiliation:‡ Department of Autoimmunity and Transplantation, Novartis Institutes for Biomedical Research (NIBR), Vienna, Austria
type:Person
name:Strobl, Herbert
affiliation:† Institute of Immunology, Center of Physiology, Pathophysiology and Immunology, Medical University Vienna, Vienna, Austria; and
type:Person
description:Abstract. The transcription factor aryl hydrocarbon receptor (AhR) represents a promising therapeutic target in allergy and autoimmunity. AhR signaling ind
pageStart:66
pageEnd:74
siteName:American Association of Immunologists
thumbnailURL:https://aai.silverchair-cdn.com/aai/content_public/journal/jimmunol/issue/183/1/2/m_jimmunol_183_1_cover.png?Expires=1814123631&Signature=AKHMrOs-lqB1dtiM8siJw3uo5tM8xQVAWkCvil8EGjCkQkKR~mViZkDHHaW8Oex~W6w5BL7Dooe58fVr8zDwwvqMqcVw4a5linww1ty9jZ-lWJIdKJkt8rsOml~D5WbJGlO~FJ5wnDYnvz4S4GJtaYRhSs3NhzjrX2bGHf34TyPjm1rLT9GBv-LvQjXuPjSztMRHAbWLUisxqK~6IGa3GdY-RrNqBstzpKB05-ccEA4cc9H9AeVzD6A0i6p8K~1c7jC9rxHGrTnKnIwI-fjP8-h1kVUajApMjXbe76jKmlbjy8pAScof2H8Cd1nMGy6slBhxR7LjNsSAeBHnxF60AA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA
headline:Aryl Hydrocarbon Receptor Activation Inhibits In Vitro Differentiation of Human Monocytes and Langerhans Dendritic Cells1
image:https://aai.silverchair-cdn.com/aai/content_public/journal/jimmunol/issue/183/1/2/m_jimmunol_183_1_cover.png?Expires=1814123631&Signature=AKHMrOs-lqB1dtiM8siJw3uo5tM8xQVAWkCvil8EGjCkQkKR~mViZkDHHaW8Oex~W6w5BL7Dooe58fVr8zDwwvqMqcVw4a5linww1ty9jZ-lWJIdKJkt8rsOml~D5WbJGlO~FJ5wnDYnvz4S4GJtaYRhSs3NhzjrX2bGHf34TyPjm1rLT9GBv-LvQjXuPjSztMRHAbWLUisxqK~6IGa3GdY-RrNqBstzpKB05-ccEA4cc9H9AeVzD6A0i6p8K~1c7jC9rxHGrTnKnIwI-fjP8-h1kVUajApMjXbe76jKmlbjy8pAScof2H8Cd1nMGy6slBhxR7LjNsSAeBHnxF60AA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA
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id:https://journals.aai.org/jimmunol/issue/183/1
issueNumber:1
datePublished:2009-07-01
isPartOf:
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name:The Journal of Immunology
issn:
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id:https://journals.aai.org/jimmunol
name:The Journal of Immunology
issn:
1550-6606
Person:
name:Platzer, Barbara
affiliation:* Division of Gastroenterology and Nutrition, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115;
name:Richter, Susanne
affiliation:† Institute of Immunology, Center of Physiology, Pathophysiology and Immunology, Medical University Vienna, Vienna, Austria; and
name:Kneidinger, Doris
affiliation:† Institute of Immunology, Center of Physiology, Pathophysiology and Immunology, Medical University Vienna, Vienna, Austria; and
name:Waltenberger, Darina
affiliation:† Institute of Immunology, Center of Physiology, Pathophysiology and Immunology, Medical University Vienna, Vienna, Austria; and
name:Woisetschläger, Maximilian
affiliation:‡ Department of Autoimmunity and Transplantation, Novartis Institutes for Biomedical Research (NIBR), Vienna, Austria
name:Strobl, Herbert
affiliation:† Institute of Immunology, Center of Physiology, Pathophysiology and Immunology, Medical University Vienna, Vienna, Austria; and
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