
DOI . ORG {
}
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- Typesetter CMS (3 occurrences)
Title[redir]:
Frontiers | Single-cell RNA sequencing analysis reveals the heterogeneity of IL-10 producing regulatory B cells in lupus-prone mice
Description:
IntroductionB cells can have both pathogenic and protective roles in autoimmune diseases, including systemic lupus erythematosus (SLE). Deficiencies in the n...
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Keywords {π}
cells, mice, cluster, cell, activedisease, predisease, bregs, disease, breg, gene, expression, clusters, figure, doi, text, google, scholar, crossref, full, analysis, subsets, abstract, regulatory, pubmed, lupus, singlecell, lupusprone, genes, active, producing, markers, autoimmunity, total, function, pbpc, compared, increased, autoimmune, populations, pcs, population, immunol, integrated, inflammatory, pbpcs, decreased, naΓ―ve, mrllpr, sets, trajectory,
Topics {βοΈ}
cd19+il10+cd21+cd24hiigm+cd23+ cd19+il10+cd21+cd24hiigm+cd23 data availability statement lupus-prone mrl/lpr mice autoimmune-prone mrl/mp-faslpr single-cell rna sequencing active-disease mrl/lpr mice single-cell rna-seq apc conjugated anti-igh pre-disease plasmablast/plasma cell single-cell sequencing technology foxp3 fixation/permeabilization kit female mrl/lpr mice single-cell transcriptional analysis ethics statement single-cell transcriptional profiles integrated single-cell analysis nih/niams grants 1r01ar073240 single-cell trajectory analysis pb-pc pre-disease clusters italy cheong-wun kim cd138+il10+ pb-pcs induced monoclonal anti-mouse antibodies integrated single-cell clusters open-access article distributed t-bet dependent manner representing class-switched pcs post-gem rt-cleanup cell biotin-antibody cocktail pre-defined cell type phagocytic pb-pc subset pre-defined gene sets class-switched pcs indicative pro-inflammatory gene signatures identify disease stage-dependent pre-defined breg subset single-cell cluster markers pb-pc gene signature lupus-prone mice andrea lupus-prone mice prior pro-cell cycle genes cell marker-annotated clusters heightened pro-inflammatory environment active-disease mice exhibited typically retain poly-reactive/ transcriptionally defined alterations pro-inflammatory environment present disease stage-dependent differences rna-seq data single-cell datasets
Questions {β}
- Marginal zone B cells: From housekeeping function to autoimmunity?
Schema {πΊοΈ}
ScholarlyArticle:
context:https://schema.org
headline:Single-cell RNA sequencing analysis reveals the heterogeneity of IL-10 producing regulatory B cells in lupus-prone mice
author:
type:Person
name:Andrea R. Daamen
affiliation:
AMPEL BioSolutions LLC and the RILITE Research Institute, United States
type:Person
name:Razan M. Alajoleen
affiliation:
Department of Biomedical Sciences and Pathology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, United States
type:Person
name:Amrie C. Grammer
affiliation:
AMPEL BioSolutions LLC and the RILITE Research Institute, United States
type:Person
name:Xin M. Luo
affiliation:
Department of Biomedical Sciences and Pathology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, United States
type:Person
name:Peter E. Lipsky
affiliation:
AMPEL BioSolutions LLC and the RILITE Research Institute, United States
datePublished:2023-12-14
dateModified:2025-07-01
publisher:
type:Organization
name:Frontiers
isPartOf:
type:PublicationIssue
datePublished:2023
isPartOf:
type:PublicationVolume
volumeNumber:14
isPartOf:
type:Periodical
name:Frontiers in Immunology
citation:
https://doi.org/10.3389/fimmu.2023.1282770
inLanguage:en
Person:
name:Andrea R. Daamen
affiliation:
AMPEL BioSolutions LLC and the RILITE Research Institute, United States
name:Razan M. Alajoleen
affiliation:
Department of Biomedical Sciences and Pathology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, United States
name:Amrie C. Grammer
affiliation:
AMPEL BioSolutions LLC and the RILITE Research Institute, United States
name:Xin M. Luo
affiliation:
Department of Biomedical Sciences and Pathology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, United States
name:Peter E. Lipsky
affiliation:
AMPEL BioSolutions LLC and the RILITE Research Institute, United States
Organization:
name:Frontiers
PublicationIssue:
datePublished:2023
isPartOf:
type:PublicationVolume
volumeNumber:14
isPartOf:
type:Periodical
name:Frontiers in Immunology
PublicationVolume:
volumeNumber:14
isPartOf:
type:Periodical
name:Frontiers in Immunology
Periodical:
name:Frontiers in Immunology
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