
DOI . ORG {
}
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Title[redir]:
Frontiers | Estrogen Receptor α Mediates Doxorubicin Sensitivity in Breast Cancer Cells by Regulating E-Cadherin
Description:
Anthracyclines resistance is commonly seen in patients with estrogen receptor α (ERα) positive breast cancer. Epithelial-mesenchymal transition (EMT), which ...
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Keywords {🔍}
cells, cancer, dox, breast, ecadherin, expression, erα, mdamb, cell, snail, twist, full, doi, abstract, text, google, scholar, treatment, pubmed, crossref, erαpositive, figure, doxorubicin, mcf, emt, erαnegative, transition, resistance, transcription, tumor, sensitivity, china, patients, epithelialmesenchymal, university, mesenchymal, chemoresistance, treated, estrogen, mcfadr, upregulated, zhang, epithelial, factors, control, detected, receptor, mouse, data, incubated,
Topics {✒️}
stat3/oct-4/c-myc signal circuit e-cadherin controls beta-catenin gemcitabine-induced epithelial-mesenchymal transition trkb-induced epithelial-mesenchymal transition downregulating estrogen receptor-alpha high-invasive erα-negative cells triple-negative breast cancer open-access article distributed erα-negative mda-mb-231 cells erα-negative mda-mb-468 cells data availability statement porta-de-la-riva erα-negative breast cancer erα-negative breast tumors erα-positive breast cancer nf-kappab transcriptional activity emt-induced transcription factors inhibit e-cadherin transcription carb-box-binding factor long-term prognostic risk mcf-7/adr cell lines anti-e-cadherin antibody e-cadherin citation drug resistance view e-cadherin gene transcription erα-negative tumor subtypes dox-resistant mcf-7/adr cells chemotherapy-induced drug resistance mouse tumor model showing mesenchymal-epithelial transition tris-buffered saline solution estrogen receptor α erα-negative mda-mb-231 erα-positive mcf-7/adr erα-positive mcf-7 cells emt-related transcription factors research search frontiers ethics statement erα-mediated emt pathway slug regulates e-cadherin zhe-sheng chen department twist-snail axis critical bogu biology company mda-mb-468 cells transfected positive breast cancer erα overexpressing cells repressing e-cadherin expression esr1 plasmids-transfected cells anthracyclines-based neoadjuvant chemotherapy breast cancer cells
Schema {🗺️}
ScholarlyArticle:
context:https://schema.org
headline:Estrogen Receptor α Mediates Doxorubicin Sensitivity in Breast Cancer Cells by Regulating E-Cadherin
author:
type:Person
name:Xiaoqing Wan
affiliation:
Laboratory of Molecular Oncology, Weifang Medical University, China
Department of Pathophysiology, Weifang Medical University, China
type:Person
name:Jiaxin Hou
affiliation:
School of Physical Education & Sports Science, Qufu Normal University, China
type:Person
name:Shurong Liu
affiliation:
Laboratory of Molecular Oncology, Weifang Medical University, China
type:Person
name:Yanli Zhang
affiliation:
Department of Pathophysiology, Weifang Medical University, China
type:Person
name:Wenqing Li
affiliation:
Laboratory of Molecular Oncology, Weifang Medical University, China
type:Person
name:Yanru Zhang
affiliation:
Laboratory of Molecular Oncology, Weifang Medical University, China
type:Person
name:Yi Ding
affiliation:
Department of Pathophysiology, Weifang Medical University, China
Key Laboratory of Applied Pharmacology, Weifang Medical University, China
datePublished:2021-02-04
dateModified:2025-07-01
publisher:
type:Organization
name:Frontiers
isPartOf:
type:PublicationIssue
datePublished:2021
isPartOf:
type:PublicationVolume
volumeNumber:9
isPartOf:
type:Periodical
name:Frontiers in Cell and Developmental Biology
citation:
https://doi.org/10.3389/fcell.2021.583572
inLanguage:en
Person:
name:Xiaoqing Wan
affiliation:
Laboratory of Molecular Oncology, Weifang Medical University, China
Department of Pathophysiology, Weifang Medical University, China
name:Jiaxin Hou
affiliation:
School of Physical Education & Sports Science, Qufu Normal University, China
name:Shurong Liu
affiliation:
Laboratory of Molecular Oncology, Weifang Medical University, China
name:Yanli Zhang
affiliation:
Department of Pathophysiology, Weifang Medical University, China
name:Wenqing Li
affiliation:
Laboratory of Molecular Oncology, Weifang Medical University, China
name:Yanru Zhang
affiliation:
Laboratory of Molecular Oncology, Weifang Medical University, China
name:Yi Ding
affiliation:
Department of Pathophysiology, Weifang Medical University, China
Key Laboratory of Applied Pharmacology, Weifang Medical University, China
Organization:
name:Frontiers
PublicationIssue:
datePublished:2021
isPartOf:
type:PublicationVolume
volumeNumber:9
isPartOf:
type:Periodical
name:Frontiers in Cell and Developmental Biology
PublicationVolume:
volumeNumber:9
isPartOf:
type:Periodical
name:Frontiers in Cell and Developmental Biology
Periodical:
name:Frontiers in Cell and Developmental Biology
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