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}
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Title[redir]:
Frontiers | The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome
Description:
T-helper 17 (Th17) and T-regulatory (Treg) cells are frequently found at barrier surfaces, particularly within the intestinal mucosa, where they function to ...
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Keywords {π}
cells, text, crossref, full, google, scholar, abstract, pubmed, cell, tregs, regulatory, intestinal, treg, foxp, differentiation, gut, immunity, immunol, responses, bacteria, commensal, inflammation, receptor, function, immune, disease, tcells, induction, microbiome, tgfΞ², inflammatory, human, colitis, mice, ibd, med, tregth, tcell, generation, nature, sfb, doijimmuni, bowel, plasticity, regulation, microbial, expression, fragilis, doinature, host,
Topics {βοΈ}
short-chain fatty acid tgf-beta-induced foxp3 inhibits short-chain fatty acids il-17-producing foxp3+cd4+ lymphocytes il-17-producing rorΞ³t+tΞ±Ξ² cells cells induce cd4+cd25-foxp3 il-17-producing t-helper cells open-access article distributed rorΞ³t+tΞ±Ξ² cells derived naΓ―ve cd4+ t-cells rorΞ³t+foxp3+ treg/th17 cells drive il-23-dependent inflammation upregulating g-protein receptor hypoxia-inducible factor 1Ξ± peripheral cd4+cd25- naive bacteria-producing ahr ligands relieve foxp3-mediated inhibition exhibits treg-inducing activity antigen-naΓ―ve t-cells t-bet-dependent manner antigen-specific peripheral shaping wild-type c57bl/6 mice adenosine monophosphate-activated kinase il-12p35-deficient mice t-betβ/βrag2β/β mice treg-specific myd88 deficiency preventing th17-mediated colitis de novo generation treg t-cell receptor foxp3 transcription-factor-dependent interest statement directing t-helper cells il-17-producing t-cells blocking il-6r expression attenuates bacteria-induced colitis microbial-activated dendritic cells aryl hydrocarbon receptor promotes t-cell differentiation cell contact-dependent immunosuppression proinflammatory t-cell responses lineage-specific transcription factors activated effector t-cells il-6-stimulated t-cells research search frontiers il-23r/il-22 pathway differentiated treg/effector cells colonic helios-negative tregs tgfΞ² represses il-23r segmented filamentous bacteria il-10-producing foxp3+ tregs
Schema {πΊοΈ}
ScholarlyArticle:
context:https://schema.org
headline:The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome
author:
type:Person
name:Sara Omenetti
affiliation:
Department of Pathology, Case Western Reserve University School of Medicine, USA
type:Person
name:Theresa T. Pizarro
affiliation:
Department of Pathology, Case Western Reserve University School of Medicine, USA
datePublished:2015-12-17
dateModified:2025-06-30
publisher:
type:Organization
name:Frontiers
isPartOf:
type:PublicationIssue
datePublished:2015
isPartOf:
type:PublicationVolume
volumeNumber:6
isPartOf:
type:Periodical
name:Frontiers in Immunology
citation:
https://doi.org/10.3389/fimmu.2015.00639
inLanguage:en
Person:
name:Sara Omenetti
affiliation:
Department of Pathology, Case Western Reserve University School of Medicine, USA
name:Theresa T. Pizarro
affiliation:
Department of Pathology, Case Western Reserve University School of Medicine, USA
Organization:
name:Frontiers
PublicationIssue:
datePublished:2015
isPartOf:
type:PublicationVolume
volumeNumber:6
isPartOf:
type:Periodical
name:Frontiers in Immunology
PublicationVolume:
volumeNumber:6
isPartOf:
type:Periodical
name:Frontiers in Immunology
Periodical:
name:Frontiers in Immunology
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