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org/cgi/content/full/db09-0955/dc1 ada journals reprints privacy policy ada journal policies mid-ventricular cross-sections clinical outcomes research high-fat diet–streptozotocin model high-frequency ultrasound imaging cd26/dipeptidyl peptidase iv mice versus wild-type diabetes study groupgerstein hc wild-type c57bl/6 mice glucose-dependent insulinotropic polypeptide dipeptidyl peptidase-iv activity wild-type hearts undergoing real-time quantitative pcr quantitative real-time pcr glp-1r agonist liraglutide subsequent clinical studies candidate pro-survival genes population-based cohort study wild-type mice treated positive end-expiratory pressure online appendix diabetes care 2007 ampk-enos-mediated signaling heme oxygenase-1 protects kaplan-meier survival analyses real-time pcr analysis nondiabetic wild-type mice stromal cell–derived factor-1 cd26/dpp-iv inhibition hfd-fed mice produced glp-1r agonists exenatide american diabetes association myocardial ischaemia-reperfusion injury clinical studies antidiabetic drug-naive patients methods animal models db/db diabetic mouse overlapping spectrum dpp4−/− mice post-mi left ventricular dysfunction glp-1r agonist nonischemic myocardium suggest nat rev endocrinol 2009 normoglycemic wild-type diabetes nutr metab 2004 latent autoimmune diabetes diabetesbio diabetes day

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ScholarlyArticle:
      context:https://schema.org
      id:https://diabetesjournals.org/diabetes/article/59/4/1063/33403/Genetic-Deletion-or-Pharmacological-Inhibition-of
      name:Genetic Deletion or Pharmacological Inhibition of Dipeptidyl Peptidase-4 Improves Cardiovascular Outcomes After Myocardial Infarction in Mice
      about:
         myocardial infarction
         metformin
         dipeptidyl-peptidase iv
         ligation
         heart
         mice
         sitagliptin
         blood glucose normal
      datePublished:2010-01-22
      isPartOf:
         id:https://diabetesjournals.org/diabetes/issue/59/4
         type:PublicationIssue
         issueNumber:4
         datePublished:2010-04-01
         isPartOf:
            id:https://diabetesjournals.org/diabetes
            type:Periodical
            name:Diabetes
            issn:
               1939-327X
      url:https://dx.doi.org/10.2337/db09-0955
      keywords:
         myocardial infarction
         metformin
         dipeptidyl-peptidase iv
         ligation
         heart
         mice
         sitagliptin
         blood glucose normal
      inLanguage:en
      copyrightHolder:American Diabetes Association
      copyrightYear:2025
      publisher:
      author:
            name:Sauvé, Meghan
            affiliation:1 Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada;
            type:Person
            name:Ban, Kiwon
            affiliation:2 Toronto General Hospital, the Heart & Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, and the Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada;
            type:Person
            name:Momen, M. Abdul
            affiliation:2 Toronto General Hospital, the Heart & Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, and the Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada;
            type:Person
            name:Zhou, Yu-Qing
            affiliation:3 Mouse Imaging Centre, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
            type:Person
            name:Henkelman, R. Mark
            affiliation:3 Mouse Imaging Centre, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
            type:Person
            name:Husain, Mansoor
            affiliation:2 Toronto General Hospital, the Heart & Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, and the Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada;
            type:Person
            name:Drucker, Daniel J.
            affiliation:1 Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada;
            type:Person
      description:OBJECTIVE. Glucagon-like peptide-1 (7-36)amide (GLP-1) is cleaved by dipeptidyl peptidase-4 (DPP-4) to GLP-1 (9-36)amide. We examined whether chemical inhi
      pageStart:1063
      pageEnd:1073
      siteName:American Diabetes Association
      thumbnailURL://ada.silverchair-cdn.com/data/SiteBuilderAssets/Live/Images/diabetes/CoverImage-367168227.png
      headline:Genetic Deletion or Pharmacological Inhibition of Dipeptidyl Peptidase-4 Improves Cardiovascular Outcomes After Myocardial Infarction in Mice
      image://ada.silverchair-cdn.com/data/SiteBuilderAssets/Live/Images/diabetes/CoverImage-367168227.png
      image:alt:
PublicationIssue:
      id:https://diabetesjournals.org/diabetes/issue/59/4
      issueNumber:4
      datePublished:2010-04-01
      isPartOf:
         id:https://diabetesjournals.org/diabetes
         type:Periodical
         name:Diabetes
         issn:
            1939-327X
Periodical:
      id:https://diabetesjournals.org/diabetes
      name:Diabetes
      issn:
         1939-327X
Person:
      name:Sauvé, Meghan
      affiliation:1 Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada;
      name:Ban, Kiwon
      affiliation:2 Toronto General Hospital, the Heart & Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, and the Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada;
      name:Momen, M. Abdul
      affiliation:2 Toronto General Hospital, the Heart & Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, and the Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada;
      name:Zhou, Yu-Qing
      affiliation:3 Mouse Imaging Centre, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
      name:Henkelman, R. Mark
      affiliation:3 Mouse Imaging Centre, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
      name:Husain, Mansoor
      affiliation:2 Toronto General Hospital, the Heart & Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, and the Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada;
      name:Drucker, Daniel J.
      affiliation:1 Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada;

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