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We began analyzing https://www.dovepress.com/hepatocellular-carcinoma-a-review-peer-reviewed-fulltext-article-JHC, but it redirected us to https://www.dovepress.com/hepatocellular-carcinoma-a-review-peer-reviewed-fulltext-article-JHC. The analysis below is for the second page.

Title[redir]:
Hepatocellular carcinoma: a review | JHC
Description:
Hepatocellular carcinoma: a review Julius Balogh,1,2 David Victor III,1,3,4 Emad H Asham,1,2 Sherilyn Gordon Burroughs,1,2 Maha Boktour,1,2 Ashish Saharia,1,2 Xian Li,1,2 R Mark Ghobrial,1,2 Howard P Monsour Jr,1,3,4 1Sherrie and Alan Conover Center for Liver Disease and Transplantation, 2Division of Transplantation, Department of Surgery, 3Department of Gastroenterology and Transplant Hepatology, 4Department of Medicine, Houston Methodist Hospital, Houston, TX, USA Abstract: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a leading cause of cancer-related death worldwide. In the United States, HCC is the ninth leading cause of cancer deaths. Despite advances in prevention techniques, screening, and new technologies in both diagnosis and treatment, incidence and mortality continue to rise. Cirrhosis remains the most important risk factor for the development of HCC regardless of etiology. Hepatitis B and C are independent risk factors for the development of cirrhosis. Alcohol consumption remains an important additional risk factor in the United States as alcohol abuse is five times higher than hepatitis C. Diagnosis is confirmed without pathologic confirmation. Screening includes both radiologic tests, such as ultrasound, computerized tomography, and magnetic resonance imaging, and serological markers such as α-fetoprotein at 6-month intervals. Multiple treatment modalities exist; however, only orthotopic liver transplantation (OLT) or surgical resection is curative. OLT is available for patients who meet or are downstaged into the Milan or University of San Francisco criteria. Additional treatment modalities include transarterial chemoembolization, radiofrequency ablation, microwave ablation, percutaneous ethanol injection, cryoablation, radiation therapy, systemic chemotherapy, and molecularly targeted therapies. Selection of a treatment modality is based on tumor size, location, extrahepatic spread, and underlying liver function. HCC is an aggressive cancer that occurs in the setting of cirrhosis and commonly presents in advanced stages. HCC can be prevented if there are appropriate measures taken, including hepatitis B virus vaccination, universal screening of blood products, use of safe injection practices, treatment and education of alcoholics and intravenous drug users, and initiation of antiviral therapy. Continued improvement in both surgical and nonsurgical approaches has demonstrated significant benefits in overall survival. While OLT remains the only curative surgical procedure, the shortage of available organs precludes this therapy for many patients with HCC. Keywords: hepatocellular carcinoma, cirrhosis, α-fetoprotein, orthotopic liver transplantation

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hcc, liver, hepatocellular, carcinoma, patients, hepatitis, risk, tumor, treatment, cancer, cirrhosis, survival, disease, resection, transplantation, screening, chronic, tumors, studies, portal, staging, advanced, hepatology, criteria, study, alcohol, virus, tace, diagnosis, incidence, increased, afp, review, mortality, hbv, years, therapy, prospective, development, surg, surgical, significant, rates, surveillance, sorafenib, states, gastroenterol, hepatol, united, ablation,

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lentil lectin-reactive alpha-fetoprotein-l3 image-guided catheter-based infusion elevated des-γ-carboxy prothrombin cross-sectional case-control study 131i-labeled-iodized oil glycogen-storage disease types including fast-track processing gov/policiesandbylaws/policies end-stage liver disease catheter-directed internal radiation dove medical press cancer-related death worldwide single-stranded rna virus manuscript login alan conover center c-induced liver cancer histology-proven hepatocellular carcinoma prospective long-term study case–control studies showing doxorubicin-eluting-bead embolization hyperinsulinaemia-diabetes-cancer link ajcc/tnm cancer staging intermediate-stage hepatocellular carcinoma traditional open surgery favored authors specific author serum α-fetoprotein levels afp exceeds cost-effectiveness early-stage hepatocellular carcinoma easl/aasld guidelines aasld practice guidelines body mass index des-γ carboxyprothrombin aflatoxin-induced hepatocellular carcinoma percutaneous ethanol injection population-based risk factors open resection hepatitis b-related hcc indocyanine dye retention age-specific hbsag seroprevalence warm humid conditions curr oncol rep drug-eluting beads sexual contact preventing neonatal transmission crit rev microbiol orthotopic liver transplantation long-term survival ensure optimal outcome infiltrative growth pattern

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Detection of hepatocellular carcinoma at advanced stages among patients in the HALT-C trial: where did surveillance fail?
No-mortality liver resection for hepatocellular carcinoma in cirrhotic and noncirrhotic patients: is there a way?
Surveillance for early diagnosis of hepatocellular carcinoma: is it effective in intermediate/advanced cirrhosis?
Sustained complete response and complications rates after radiofrequncy ablation of very early hepatocellular carcinoma in cirrhosis: is resection still the treatment of choice?
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