
DOI . ORG {
}
Title[redir]:
A small molecule inhibitor MCC950 ameliorates kidney injury in diabeti | DMSO
Description:
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation
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Keywords {馃攳}
mcc, mice, dbdb, renal, nlrp, cells, mesangial, inflammasome, expression, glomerular, figure, fibrosis, diabetic, cell, treatment, kidney, activation, il尾, injury, podocyte, urinary, caspase, glucose, levels, collagen, nephropathy, weeks, tgf尾, dbm, group, 伪sma, inflammation, blood, protein, tubular, fibronectin, age, inhibited, china, decreased, versus, type, staining, sem, diabetes, ratio, acr, function, markers, hginduced,
Topics {鉁掞笍}
alcohol-formalin-acetic acid solution phosphor-nuclear factor-魏b p65 upregulating nlrp3/caspase-1/il-1尾 pathway phosphatidylinositol 3-kinase/akt/mammalian target inhibiting nlrp3/caspase-1/il-1尾 pathway investigate nlpr3/caspase-1/il-1尾 expression induces pro-il-1尾 maturation nlpr3/caspase-1/il-1尾 expression heat-mediated antigen retrieval p-nf-魏b immunohistochemistry staining chronic low-grade inflammation il-1beta-dependent responses forward 5使-caacaattcctggcgttaccttgg-3使 forward 5使-atgaggaggtccaaatcg-3使 forward 5使-tgccgtgacctcaagatgtg-3使 forward 5使-gagaccttcaacaccccagc-3使 forward 5使-atggtggaccgcaacaac-3使 forward 5使-acggtggcaactcaaac-3使 forward 5使-aaacgggagggcgagtg-3使 forward 5使- ggagattactgccctggctcctagc-3使 nlrp3 inflammasome-mediated inflammation reverse 5使-gaaagccctgtattccgtctcctt-3使 reverse 5使-gaacggcgtccaagag-3使 reverse 5使-cacaagcgtgctgtaggtga-3使 reverse 5使-atgtcacgcacgatttccc-3使 reverse 5使-gagcactgaagcgaaagc-3使 reverse 5使-gggaagtggcacaagg-3使 reverse 5使-cataggacatctgggaagcaa-3使 reverse 5使-ggccggactcatcgtactcctgctt-3使 urokinase-type plasminogen activator hg-induced mesangial cells inflammatory caspase-related pyroptosis nucleotide-binding oligomerization domain including fast-track processing nlrp3-driven islet inflammation cholestatic liver injury dove medical press specific author c57blks/j-leprdb/leprdb small-molecule inhibitor end-stage renal disease 伪-smooth muscle actin p-nf-魏b staining manuscript login 12-hr light/dark cycle diabetic male db/db 2blood purification center mature il-1尾 p17 kw/bw ratio showed nlrp3 inflammasome-mediated
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