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  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
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We began analyzing https://www.dovepress.com/gut-microbiota-cognitive-frailty-and-dementia-in-older-individuals-a-s-peer-reviewed-fulltext-article-CIA, but it redirected us to https://www.dovepress.com/gut-microbiota-cognitive-frailty-and-dementia-in-older-individuals-a-s-peer-reviewed-fulltext-article-CIA. The analysis below is for the second page.

Title[redir]:
Gut microbiota, cognitive frailty and dementia in older individuals: a | CIA
Description:
Gut microbiota, cognitive frailty and dementia in older individuals: a systematic review Andrea Ticinesi,1–3 Claudio Tana,2 Antonio Nouvenne,2,3 Beatrice Prati,2 Fulvio Lauretani,2 Tiziana Meschi1–3 1Department of Medicine and Surgery, University of Parma, Parma, Italy; 2Geriatric-Rehabilitation Department, Parma University Hospital, Parma, Italy; 3Microbiome Research Hub, University of Parma, Parma, Italy Abstract: Cognitive frailty, defined as the coexistence of mild cognitive impairment symptoms and physical frailty phenotype in older persons, is increasingly considered the main geriatric condition predisposing to dementia. Recent studies have demonstrated that gut microbiota may be involved in frailty physiopathology by promoting chronic inflammation and anabolic resistance. The contribution of gut microbiota to the development of cognitive impairment and dementia is less defined, even though the concept of “gut–brain axis” has been well demonstrated for other neuropsychiatric disorders. The aim of this systematic review was to summarize the current state-of-the-art literature on the gut microbiota alterations associated with cognitive frailty, mild cognitive impairment and dementia and elucidate the effects of pre- or probiotic administration on cognitive symptom modulation in animal models of aging and human beings. We identified 47 papers with original data (31 from animal studies and 16 from human studies) suitable for inclusion according to our aims. We concluded that several observational and intervention studies performed in animal models of dementia (mainly Alzheimer’s disease) support the concept of a gut–brain regulation of cognitive symptoms. Modulation of vagal activity and bacterial synthesis of substances active on host neural metabolism, inflammation and amyloid deposition are the main mechanisms involved in this physiopathologic link. Conversely, there is a substantial lack of human data, both from observational and intervention studies, preventing to formulate any clinical recommendation on this topic. Gut microbiota modulation of cognitive function represents, however, a promising area of research for identifying novel preventive and treatment strategies against dementia. Keywords: microbiome, Alzheimer’s disease, vascular dementia, mild cognitive impairment, dysbiosis

Matching Content Categories {📚}

  • Health & Fitness
  • Education
  • Science

Content Management System {📝}

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Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 75,579,999 visitors per month in the current month.

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How Does Doi.org Make Money? {💸}

We're unsure how the site profits.

Not all websites focus on profit; some are designed to educate, connect people, or share useful tools. People create websites for numerous reasons. And this could be one such example. Doi.org could have a money-making trick up its sleeve, but it's undetectable for now.

Keywords {🔍}

microbiota, gut, cognitive, frailty, dementia, alzheimers, studies, disease, brain, impairment, aging, clinical, patients, microbiome, axis, function, dysbiosis, models, human, study, composition, role, older, gutbrain, sci, animal, dis, review, microbial, inflammation, effects, probiotics, mice, intervention, involved, administration, amyloid, research, med, symptoms, physical, development, alterations, modulation, physiopathologic, presence, dietary, fecal, systemic, diet,

Topics {✒️}

n-methyl-d-aspartic acid open-label intervention study biotic/abiotic stress-driven alzheimer gram-negative bacteria–derived lipopolysaccharide β-n-methylamino-alanine transgenic app/ps1 breed putative “gut–brain axis” bacteria-derived membrane vesicles understanding brain–gut–microbiome connections brain-derived neurotrophic factor dove medical press produce indole-3-propionic acid community-dwelling older adults short-chain fatty acids red raspberry-derived anthocyanins including fast-track processing obese-insulin resistant rats gut–liver–brain axis improve β-amyloid aggregation nationwide population-based study altered gut–brain axis post-stroke immune response bacteria–gut–brain signals antibiotic-induced gut dysbiosis microbiota–gut–brain axis gut microbiota–brain communication placebo-controlled study design late-life cognitive disorders gut–brain axis involved microbiome–gut–brain axis irritable bowel syndrome manuscript login western-style diet represents diet-induced obese mice gut microbiota-derived metabolites real-world clinical settings dementia “gut–brain axis” disease β-amyloid oligomerization neural anti-inflammatory activity tumor necrosis factor favored authors gut microbiota-derived butyrate long-term dietary habits influence β-amyloid deposition skeletal muscle size �gut–muscle axis” gut–muscle axis specific author single complex phenotype molecular mimicry involving

Questions {❓}

  • Aging gut microbiota at the cross-road between nutrition, physical frailty, and sarcopenia: is there a gut–muscle axis?
  • Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1?
  • Is Alzheimer’s disease a systemic disease?
  • Lost in translation?
  • The association between BMI and different frailty domains: a U-shaped curve?
  • The neuropharmacology of butyrate: the bread and butter of the microbiota–gut–brain axis?
  • Thinking outside the brain for cognitive improvement: is peripheral immunomodulation on the way?
  • Why publish with us?

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External Links {🔗}(317)

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Libraries {📚}

  • jQuery

Emails and Hosting {✉️}

Mail Servers:

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  • josh.ns.cloudflare.com
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CDN Services {📦}

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6.25s.