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DOI . ORG {}

Detected CMS Systems:

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Social Networks
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://journals.lww.com/jasn/abstract/2015/06000/a_single_gene_cause_in_29_5__of_cases_of.10.aspx, but it redirected us to https://journals.lww.com/jasn/abstract/2015/06000/a_single_gene_cause_in_29_5__of_cases_of.10.aspx. The analysis below is for the second page.

Title[redir]:
Journal of the American Society of Nephrology
Description:
d its age distribution in large cohorts are unknown. We performed exon sequencing of NPHS2 and WT1 for 1783 unrelated, international families with SRNS. We then examined all patients by microfluidic multiplex PCR and next-generation sequencing for all 27 genes known to cause SRNS if mutated. We detected a single-gene cause in 29.5% (526 of 1783) of families with SRNS that manifested before 25 years of age. The fraction of families in whom a single-gene cause was identified inversely correlated with age of onset. Within clinically relevant age groups, the fraction of families with detection of the single-gene cause was as follows: onset in the first 3 months of life (69.4%), between 4 and 12 months old (49.7%), between 1 and 6 years old (25.3%), between 7 and 12 years old (17.8%), and between 13 and 18 years old (10.8%). For PLCE1, specific mutations correlated with age of onset. Notably, 1% of individuals carried mutations in genes that function within the coenzyme Q10 biosynthesis pathway, suggesting that SRNS may be treatable in these individuals. Our study results should facilitate molecular genetic diagnostics of SRNS, etiologic classification for therapeutic studies, generation of genotype-phenotype correlations, and the identification of individuals in whom a targeted treatment for SRNS may be available....

Matching Content Categories {📚}

  • Health & Fitness
  • Science
  • Education

Content Management System {📝}

What CMS is doi.org built with?


Doi.org is powered by MYBB.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 76,073,390 visitors per month in the current month.

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We don’t know how the website earns money.

Not all websites are made for profit; some exist to inform or educate users. Or any other reason why people make websites. And this might be the case. Doi.org has a secret sauce for making money, but we can't detect it yet.

Keywords {🔍}

srns, journal, singlegene, age, issue, alerts, families, years, access, asn, subscribe, authors, abstract, treatment, onset, individuals, jasn, log, register, articles, steroidresistant, nephrotic, syndrome, study, author, society, buy, life, disease, identification, sequencing, genes, fraction, correlated, months, mutations, genetic, copyright, published, wolters, kluwer, health, rights, reserved, text, subscribers, member, request, content, submit,

Topics {✒️}

journal authors submit wolters kluwer health open access policy etoc alerts full text access journal tables individual subscribers log issue microfluidic multiplex pcr identified inversely correlated specific mutations correlated genotype-phenotype correlations read differentiating primary autoantibodies targeting nephrin renal tubule back print rss feeds artificial intelligence training performed exon sequencing minimal change disease journal individuals carried mutations single-gene causation service request 800-638-3030 authors register subscribe study results previous abstract published content 1681/asn website subscribe american society disease mechanisms single-gene heon yung vega-warner el-desoky large cohorts generation sequencing etiologic classification therapeutic studies copyright © 2015 rights reserved secondary fsgs iga nephropathy glomerular diseases email inbox data mining age distribution effective treatment

Questions {❓}

  • Not a Subscriber?

Social Networks {👍}(4)

External Links {🔗}(70)

Analytics and Tracking {📊}

  • Comscore
  • Google Analytics
  • Google Tag Manager
  • Mouseflow

Libraries {📚}

  • Bootstrap
  • FontAwesome
  • jQuery
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
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Name Servers:

  • josh.ns.cloudflare.com
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CDN Services {📦}

  • Cookielaw
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  • Scite
  • Wolterskluwer

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