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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Social Networks
  9. External Links
  10. Analytics And Tracking
  11. Libraries
  12. Hosting Providers
  13. CDN Services

We began analyzing https://jkcvhl.com/index.php/jkcvhl/article/view/44, but it redirected us to https://jkcvhl.com/index.php/jkcvhl/article/view/44. The analysis below is for the second page.

Title[redir]:
The Potential Role of Lysosomal Sequestration in Sunitinib Resistance of Renal Cell Cancer | Journal of Kidney Cancer
Description:
Renal cell carcinoma (RCC) is a highly vascularized tumor type, which is often associated with inactivated mutations in the von Hippel-Lindau gene that drives proangiogenic signaling pathways. As such, new therapies for the treatment of RCC have largely been focused on blocking angiogenesis. Sunitinib, an antiangiogenic tyrosine kinase inhibitor, is the most frequently used first-line drug for the treatment of RCC. Although treatment with sunitinib improves patient outcome considerably, acquired resistance will emerge in all cases. The molecular mechanisms of resistance to sunitinib are poorly understood, but in the past decade, several of these have been proposed. Lysosomal sequestration of sunitinib was reported as a potential resistance mechanism to sunitinib. In this review, the underlying molecular mechanisms of lysosomal sunitinib sequestration and the potential strategies to overcome this resistance are discussed to be able to further improve the treatment of RCC.

Matching Content Categories {📚}

  • Science
  • Health & Fitness
  • Telecommunications

Content Management System {📝}

What CMS is doi.org built with?

Website use Open Journal Systems 3.4.0.6.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 75,480,999 visitors per month in the current month.

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How Does Doi.org Make Money? {💸}

We can't figure out the monetization strategy.

Some websites aren't about earning revenue; they're built to connect communities or raise awareness. There are numerous motivations behind creating websites. This might be one of them. Doi.org could have a money-making trick up its sleeve, but it's undetectable for now.

Keywords {🔍}

cancer, sunitinib, resistance, cell, renal, carcinoma, kidney, lysosomal, sequestration, journal, vhl, medical, treatment, potential, metastatic, review, gotink, drug, rcc, tumor, kinase, mechanism, therapy, clin, content, main, home, role, article, department, oncology, university, center, amsterdam, netherlands, lysosomes, inhibitor, molecular, mechanisms, oncol, haas, dekker, honeywell, nat, growth, factor, patients, cells, httpsdoiorgjkcvhl, sidebar,

Topics {✒️}

gov/ct2/show/results/nct00083889 14 drug-sensitive mes-sa von hippel-lindau gene su011248 versus interferon-alfa inhibit multidrug resistance immortalized human hepatocytes metastatic renal carcinoma hepatocellular carcinoma cells renal cell carcinoma renal-cell carcinoma renal cell cancer clinical kinase inhibitors kinase inhibitor selectivity cell death dis cancer treat rev mol cancer ther dall'oglio mf donalisio da silva fda approval summary differentiated locally advanced biggs wh 3rd biochim biophys acta drug metab dispos kidney cancer vhl de haas rr clin cancer res axl overcomes resistance q3-oncology -rank 242/326 clinical trials website chemotherapy resistance mechanism van beijnum jr 44 article details affecting sunitinib biodistribution lysosomally sequestered sunitinib line systemic therapy underlying molecular mechanisms potential resistance mechanism renal carcinoma current status lysosomal sunitinib sequestration gotink department verheul department fa2n-4 cells kidney cancer cell oncol cell physiol tumor microvasculature vascular occlusion line drug medical oncology

Social Networks {👍}(6)

External Links {🔗}(59)

Analytics and Tracking {📊}

  • Google Analytics
  • Google Analytics 4
  • Google Tag Manager
  • Google Universal Analytics

Libraries {📚}

  • Bootstrap
  • FontAwesome
  • jQuery
  • jQuery module (jquery)

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Cloudflare
  • Jsdelivr

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