DOI . ORG {
}
Detected CMS Systems:
- Wordpress (1 occurrences)
- Hubspot (1 occurrences)
We began analyzing https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003707, but it redirected us to https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003707. The analysis below is for the second page.
Title[redir]:
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Description:
Author Summary Sexually transmitted infections caused by Chlamydia are increasing every year in the US and an effective vaccine is urgently required. Unfortunately, we currently only have a rudimentary understanding of the natural host immune response to Chlamydia infection, especially in the context of the female genital tract. Here, we have developed new reagents that allow direct visualization of the host T cell responses to vaginal Chlamydia infection using a mouse model of infection. These new tools reveal an unexpectedly complex CD4 T cell response to infection and a surprising role for B cells in preventing the spread of bacteria to multiple host tissues. This greater understanding of the host response to infection may eventually allow the construction of an effective vaccine.
Title[redir]:
No title found...
Description:
Author Summary Sexually transmitted infections caused by Chlamydia are increasing every year in the US and an effective vaccine is urgently required. Unfortunately, we currently only have a rudimentary understanding of the natural host immune response to Chlamydia infection, especially in the context of the female genital tract. Here, we have developed new reagents that allow direct visualization of the host T cell responses to vaginal Chlamydia infection using a mouse model of infection. These new tools reveal an unexpectedly complex CD4 T cell response to infection and a surprising role for B cells in preventing the spread of bacteria to multiple host tissues. This greater understanding of the host response to infection may eventually allow the construction of an effective vaccine.
Matching Content Categories {📚}
- Science
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Content Management System {📝}
What CMS is doi.org built with?
Doi.org operates using WORDPRESS.
But there are also traces of other content systems on the page (hubspot).
Traffic Estimate {📈}
What is the average monthly size of doi.org audience?
🌍 Impressive Traffic: 500k - 1M visitors per month
Based on our best estimate, this website will receive around 600,019 visitors per month in the current month.
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How Does Doi.org Make Money? {💸}
We see no obvious way the site makes money.
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Keywords {🔍}
cells, infection, chlamydia, mice, cell, article, view, google, scholar, genital, tract, muridarum, chlamydiaspecific, infected, fig, immunity, μmt, lymph, spleen, data, trachomatis, response, local, bacterial, plos, expansion, bacteria, nodes, tetramers, ascites, detected, priming, systemic, number, dissemination, days, responses, pmpgspecific, journal, antigenspecific, tbet, post, pmpg, endogenous, infections, vaginal, draining, cbl, image, morrison,
Topics {✒️}
cd11b−cd11c−f4/80−b220−cd3+cd4+ cells cd11b−cd11c−f4/80−b220−cd3+cd8+ cells ifn-gamma/interleukin-17 double-positive cd4+ f4/80−gr-1−cd11b−b220−cd4+cd44hipmpg-1303–311 unexpectedly complex cd4 plos pathogens 8 plos pathogens 7 f4/80−gr-1−cd11b−b220−cd4+ f4/80−gr-1−cd11b−b220−cd8+ plos pathog 9 cookies plos th1/treg/th17 cell subsets mouse models reflects open-access article distributed mhc class-ii tetramers pmhc class-ii tetramers ifn-γ-secreting cd4 fitz-hugh-curtis syndrome 1-step nbt/bcip substrate gov/std/stats11/surv2011 staining included fitc-cd11b short-lived th17 cells biotinylated anti-ifn-γ lineage-specific transcription factors impaired antigen-specific cd4 ifn-gamma-mediated inhibition original author flagellin-specific th17 cells chlamydia-specific memory cd4 murine models protein-rich lymphocytic ascites tracking salmonella-specific cd4 ifn-γ-producing cd4+ polyclonal antigen-specific cd4 rorγt-gfp reporter mice anti-fluorochrome magnetic beads anti-chlamydia momp antibody health purified anti-ifn-γ anti-cd4 magnetic beads chlamydia-specific th17 cells cells producing ifn-γ stable chlamydia-specific cd4 local chlamydia-specific cd4 pre-determined optimal ratio days post immunization/infection biotinylated i-ab monomers infection models [23] cells expressed t-bet b-cell-deficient mice
Questions {❓}
- Gottlieb SL, Berman SM, Low N (2010) Screening and treatment to prevent sequelae in women with Chlamydia trachomatis genital infection: how much do we know?
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