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DOI . ORG {}

Detected CMS Systems:

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Wordpress Themes And Plugins
  7. Keywords
  8. Topics
  9. Questions
  10. Social Networks
  11. External Links
  12. Analytics And Tracking
  13. Libraries
  14. Hosting Providers
  15. CDN Services

We began analyzing https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038863, but it redirected us to https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038863. The analysis below is for the second page.

Title[redir]:
No title found...
Description:
Similar to other malignancies, urothelial carcinoma (UC) is characterized by specific recurrent chromosomal aberrations and gene mutations. However, the interconnection between specific genomic alterations, and how patterns of chromosomal alterations adhere to different molecular subgroups of UC, is less clear. We applied tiling resolution array CGH to 146 cases of UC and identified a number of regions harboring recurrent focal genomic amplifications and deletions. Several potential oncogenes were included in the amplified regions, including known oncogenes like E2F3, CCND1, and CCNE1, as well as new candidate genes, such as SETDB1 (1q21), and BCL2L1 (20q11). We next combined genome profiling with global gene expression, gene mutation, and protein expression data and identified two major genomic circuits operating in urothelial carcinoma. The first circuit was characterized by FGFR3 alterations, overexpression of CCND1, and 9q and CDKN2A deletions. The second circuit was defined by E3F3 amplifications and RB1 deletions, as well as gains of 5p, deletions at PTEN and 2q36, 16q, 20q, and elevated CDKN2A levels. TP53/MDM2 alterations were common for advanced tumors within the two circuits. Our data also suggest a possible RAS/RAF circuit. The tumors with worst prognosis showed a gene expression profile that indicated a keratinized phenotype. Taken together, our integrative approach revealed at least two separate networks of genomic alterations linked to the molecular diversity seen in UC, and that these circuits may reflect distinct pathways of tumor development.

Matching Content Categories {📚}

  • Education
  • Science
  • Photography

Content Management System {📝}

What CMS is doi.org built with?


Doi.org uses WORDPRESS. But there are also traces of other content systems on the page (hubspot).

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌍 Impressive Traffic: 500k - 1M visitors per month


Based on our best estimate, this website will receive around 600,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Doi.org Make Money? {💸}

We don't see any clear sign of profit-making.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Doi.org could have a money-making trick up its sleeve, but it's undetectable for now.

Wordpress Themes and Plugins {🎨}

What WordPress theme does this site use?

It is strange but we were not able to detect any theme on the page.

What WordPress plugins does this website use?

It is strange but we were not able to detect any plugins on the page.

Keywords {🔍}

expression, genomic, tumors, alterations, gene, deletions, figure, fgfr, samples, data, recurrent, number, cdkna, article, mutations, amplifications, view, regions, google, scholar, tumor, cases, genes, analysis, cancer, observed, high, ccnd, circuit, defined, plos, bladder, tpmdm, chromosome, chromosomal, gains, copy, relative, red, fgas, group, molecular, subgroups, pten, showed, low, image, significant, urothelial, specific,

Topics {✒️}

cookies plos plos contributed reagents/materials/analysis tools open-access article distributed 1999 classification systems uk/humgen/cnv/data/cnv_data/ genomically complex complex genomes nature genetics 43 tiling-resolution bac arrays hierarchical cluster analyses hierarchical cluster analysis larger sample material original author global gene expression pair-wise hypergeometric tests share central features base–2nd generation software positive tumor cells/nuclei aberrant e2f3/rb1 expression genome-wide screening bladder cancer stage combined genome profiling human bladder cancer dna copy number recurrent high-level amplifications raf1/ras alterations showed tp53/mdm2 alteration status comparative genomic hybridization clinical cancer research relative expression levels copy number gain sciblu genomics centre hemizygous/homozygous cdkn2a deletions gene expression profiling tiling resolution acgh dna excision repair local ethical committee detailed sample information p16 protein expression copy number alterations methods sample acquisition relative gene expression segmented genomic profiles copy-number variants swedish cancer society positive tumor nuclei elevated expression relative array-based cgh ten focal events

Questions {❓}

  • Goebell PJ, Knowles MA (2010) Bladder cancer or bladder cancers?

Social Networks {👍}(3)

External Links {🔗}(179)

Analytics and Tracking {📊}

  • Facebook Pixel
  • Google Analytics
  • Google Analytics 4
  • Google Tag Manager
  • Google Universal Analytics
  • HubSpot

Libraries {📚}

  • Foundation
  • jQuery
  • Leaflet
  • Lightbox
  • Modernizr
  • Moment.js
  • Underscore.js
  • Video.js
  • Vue.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Cloudflare
  • Crossref

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