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Title[redir]:
Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes | PLOS Genetics
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Keywords {🔍}
genes, functional, variation, intolerance, disease, view, genetic, article, personal, genomes, mutations, plos, cookies, system, cookie, petrovski, interpreting, scoring, common, variants, data, exome, show, author, human, terms, types, publish, research, genic, interpretation, wang, heinzen, allen, goldstein, made, impact, found, carry, healthy, individuals, judged, kinds, develop, tolerate, genomewide, nhlbi, sequencing, project, based,
Topics {✒️}
open-access article distributed genome-wide scoring system view correction abstract media inquiries plos medical research council download citation email genome-wide scale standing genetic variation tolerate functional variation interpreting personal genomes identifying pathogenic mutations functional genetic variation intolerance ranking system early career fellow common functional variation intolerance scoring system exome sequences made cookie preference center save selected preferences common functional variants disorder classes defined competing interests exist human disease network ranks human genes author summary original author cookie policy genic intolerance information personal genomes functional impact disease causing genes functional variation plos genet 9 intolerance score top back cookies plos genetic disease striking variation article sequence data data collection competing interests cookie preferences human population authors individual mutations genes causing central challenge healthy individuals
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