Here's how DOI.ORG makes money* and how much!

*Please read our disclaimer before using our estimates.
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DOI . ORG {}

Detected CMS Systems:

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Wordpress Themes And Plugins
  7. Keywords
  8. Topics
  9. Social Networks
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003336, but it redirected us to https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003336. The analysis below is for the second page.

Title[redir]:
No title found...
Description:
Author Summary Systemic lupus erythematosus (SLE) is a debilitating autoimmune disease contributed to by excessive innate immune activation involving toll-like receptors (TLRs, particularly TLR7/8/9) and type I interferon (IFN) signaling pathways. TLR7 responds against RNA–containing nuclear antigens and activates IFN-α pathway, playing a pivotal role in the development of SLE. While a genomic duplication of Tlr7 promotes lupus-like disease in the Y-linked autoimmune accelerator (Yaa) murine model, the lack of common copy number variations at TLR7 in humans led us to identify a functional single nucleotide polymorphism (SNP), rs3853839 at 3′ UTR of the TLR7 gene, associated with SLE susceptibility in Eastern Asians. In this study, we fine-mapped the TLR7-TLR8 region and confirmed rs3853839 exhibiting the strongest association with SLE in European Americans, African Americans, and Amerindian/Hispanics. Individuals carrying the risk G allele of rs3853839 exhibited increased TLR7 expression at the both mRNA and protein level and decreased transcript degradation. MicroRNA-3148 (miR-3148) downregulated the expression of non-risk allele (C) containing transcripts preferentially, suggesting a likely mechanism for increased TLR7 levels in risk-allele carriers. This trans-ancestral mapping provides evidence for the global association with SLE risk at rs3853839, which resides in a microRNA–gene regulatory site affecting TLR7 expression.

Matching Content Categories {📚}

  • Education
  • Science
  • Real Estate

Content Management System {📝}

What CMS is doi.org built with?


Doi.org uses WORDPRESS. But there are also traces of other content systems on the page (hubspot).

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 76,079,999 visitors per month in the current month.

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How Does Doi.org Make Money? {💸}

We can't see how the site brings in money.

Earning money isn't the goal of every website; some are designed to offer support or promote social causes. People have different reasons for creating websites. This might be one such reason. Doi.org might be earning cash quietly, but we haven't detected the monetization method.

Wordpress Themes and Plugins {🎨}

What WordPress theme does this site use?

It is strange but we were not able to detect any theme on the page.

What WordPress plugins does this website use?

It is strange but we were not able to detect any plugins on the page.

Keywords {🔍}

tlr, association, sle, expression, allele, article, view, scholar, google, pbmcs, lupus, figure, levels, snps, systemic, mrna, luciferase, cells, study, plos, erythematosus, snp, region, utr, cell, data, tlrtlr, gene, controls, test, phd, allelic, ratio, ancestries, genetic, studies, control, tolllike, individuals, risk, effect, women, argentina, reporter, showed, genet, men, americans, carriers, variants,

Topics {✒️}

public health genomics messenger rna contributed reagents/materials/analysis tools open-access article distributed plos genet 9 plos genet 6 plos genet 8 plos genet 4 plos genet 5 health grants cookies plos plos health global gene expression autoimmune diseases systemic lupus erythematosus–focus infectious diseases [28] rna-sensing receptors conjugated anti-human cd14 conjugated anti-human cd3 conducted trans-ancestral fine-mapping rna-related antigens due fluorochrome-matched control antibodies hospital san martín significant dose-dependent decrease complex conjugated anti-human cd19 quantitative real-time pcr y-linked autoimmune accelerator systemic lupus erythematosus b-cell gene bank1 global association global ancestry original author genome-wide association scan fluorescence-activated cell sorter mir3148-mediated tlr7 expression human genetics renilla/firefly luciferase ratio trans-ancestral meta-analysis current fine-mapping study distinct ancestries share x-linked gene tlr7 recent genome-wide association gian-domenico sebastiani md servicio de reumatología tlr7 promotes lupus cellular micro-rna nc-treated reporter vector genome-wide association studies

Social Networks {👍}(3)

External Links {🔗}(185)

Analytics and Tracking {📊}

  • Facebook Pixel
  • Google Analytics
  • Google Analytics 4
  • Google Tag Manager
  • Google Universal Analytics
  • HubSpot

Libraries {📚}

  • Foundation
  • jQuery
  • Leaflet
  • Lightbox
  • Modernizr
  • Moment.js
  • Underscore.js
  • Video.js
  • Vue.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Cloudflare
  • Crossref

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