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Title[redir]:
The Wnt Receptor Ryk Reduces Neuronal and Cell Survival Capacity by Repressing FOXO Activity During the Early Phases of Mutant Huntingtin Pathogenicity | PLOS Biology
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🌍 Impressive Traffic: 500k - 1M visitors per month
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Keywords {🔍}
neuronal, ryk, cell, foxo, disease, supported, activity, mutant, view, neurons, author, article, wnt, early, phases, rykicd, stress, plos, cookies, receptor, survival, neurodegenerative, cookie, capacity, repressing, huntingtin, tourette, christian, protein, intracellular, pathway, role, htt, models, huntingtons, cells, increased, inserm, france, foundation, manuscript, competing, interests, information, publish, reduces, pathogenicity, farina, vazquezmanrique, orfila,
Topics {✒️}
conseil regional ile-de-france including γ-secretase cleavage open-access article distributed longevity-promoting factor foxo canonical wnt/ryk signaling abolished β-catenin protection evolutionary-conserved protein important agence-nationale-recherche media inquiries plos regulate neuronal homeostasis view correction abstract full-length ryk wnt receptor ryk mutant huntingtin pathogenicity factor β-catenin download citation email cell survival/longevity involves neuronal dysfunction c-terminal fragment ryk repress activity ryk-icd fragment mutant protein expression repressing foxo activity cell survival capacity chronic stress induced young researcher award poste vert fellowship flow cytometry facility forkhead responsive element nitric oxide synthase ryk-dependent pathway cell death vulnerability author contributions amyloid precursor protein association huntington france ryk-icd pathway anne-marie orfila cookie preference center save selected preferences mutant htt cells mutant polyglutamine neurons neuronal differentiation lin-18/ryk loss early-stage increase expanded-polyq nematodes vazquez-manrique rp grants anr-08-mnps-024-01 hd neuron survival competing interests exist hereditary disease foundation
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