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Analysis across the genome of patterns of DNA methylation reveals a rich landscape of allele-specific epigenetic modification and consequent effects on allele-specific gene expression.
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Keywords {🔍}
methylation, cpg, genome, dna, figure, human, methylome, analysis, genes, level, article, view, sequencing, pbmc, asm, google, scholar, genomic, sites, cells, regions, hdmrs, expression, cpgs, data, cytosines, methylated, gene, noncpg, httpsdoiorgjournalpbios, bisulfite, levels, allelespecific, plos, number, table, fold, distribution, rate, features, sequence, defined, observed, haploid, imprinted, eps, blood, differentially, bases, alignment,
Topics {✒️}
integrative biology human health plos biol 8 plos genet 4 cookies plos public data genomics contributed reagents/materials/analysis tools open-access article distributed global analysis bi-allelic sequence information global assessment testis-specific gene encoding sequence-dependent asm [24] paired-end sequence data regulating gene expression allele-specific methylation analysis single base-pair resolution assess allele-specific methylation gov/geo/query/acc study genome-wide differences bs-treatment nucleotide conversion cytosine guanine dinucleotide copy number larger cpg cytosine methylation allele-specific methylated genes genome-wide association studies large-scale epigenomics studies display allele-specific methylation sharp intron-exon boundaries evolutionary sequence divergence sequence alignment human blood cells allele-specific expression total q14-covering bases embryonic stem cells testis-specific gene yh sequence data diploid genome sequence single-base resolution genome bs-seq approach bi-allelic information lower-cpg-density regions dna methylation profiling dna methylation analysis differential allelic expression genomic imprinting [20] genomic imprinting expression profile arising gene-body methylation
Questions {❓}
- Hayatsu H, Tsuji K, Negishi K (2006) Does urea promote the bisulfite-mediated deamination of cytosine in DNA?
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