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DOI . ORG {}

Detected CMS Systems:

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Wordpress Themes And Plugins
  7. Keywords
  8. Topics
  9. Questions
  10. Social Networks
  11. External Links
  12. Analytics And Tracking
  13. Libraries
  14. Hosting Providers
  15. CDN Services

We began analyzing https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147198, but it redirected us to https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147198. The analysis below is for the second page.

Title[redir]:
No title found...
Description:
Background A longstanding goal in regenerative medicine is to reconstitute functional tissus or organs after injury or disease. Attention has focused on the identification and relative contribution of tissue specific stem cells to the regeneration process. Relatively little is known about how the physiological process is regulated by other tissue constituents. Numerous injury models are used to investigate tissue regeneration, however, these models are often poorly understood. Specifically, for skeletal muscle regeneration several models are reported in the literature, yet the relative impact on muscle physiology and the distinct cells types have not been extensively characterised. Methods We have used transgenic Tg:Pax7nGFP and Flk1GFP/+ mouse models to respectively count the number of muscle stem (satellite) cells (SC) and number/shape of vessels by confocal microscopy. We performed histological and immunostainings to assess the differences in the key regeneration steps. Infiltration of immune cells, chemokines and cytokines production was assessed in vivo by Luminex®. Results We compared the 4 most commonly used injury models i.e. freeze injury (FI), barium chloride (BaCl2), notexin (NTX) and cardiotoxin (CTX). The FI was the most damaging. In this model, up to 96% of the SCs are destroyed with their surrounding environment (basal lamina and vasculature) leaving a “dead zone” devoid of viable cells. The regeneration process itself is fulfilled in all 4 models with virtually no fibrosis 28 days post-injury, except in the FI model. Inflammatory cells return to basal levels in the CTX, BaCl2 but still significantly high 1-month post-injury in the FI and NTX models. Interestingly the number of SC returned to normal only in the FI, 1-month post-injury, with SCs that are still cycling up to 3-months after the induction of the injury in the other models. Conclusions Our studies show that the nature of the injury model should be chosen carefully depending on the experimental design and desired outcome. Although in all models the muscle regenerates completely, the trajectories of the regenerative process vary considerably. Furthermore, we show that histological parameters are not wholly sufficient to declare that regeneration is complete as molecular alterations (e.g. cycling SCs, cytokines) could have a major persistent impact.

Matching Content Categories {📚}

  • Health & Fitness
  • Fitness & Wellness
  • Science

Content Management System {📝}

What CMS is doi.org built with?


Doi.org is built with WORDPRESS. But there are also traces of other content systems on the page (hubspot).

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌍 Impressive Traffic: 500k - 1M visitors per month


Based on our best estimate, this website will receive around 600,019 visitors per month in the current month.
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How Does Doi.org Make Money? {💸}

We're unsure how the site profits.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Doi.org might be cashing in, but we can't detect the method they're using.

Wordpress Themes and Plugins {🎨}

What WordPress theme does this site use?

It is strange but we were not able to detect any theme on the page.

What WordPress plugins does this website use?

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Keywords {🔍}

injury, muscle, cells, days, month, cell, satellite, fig, regeneration, models, number, postinjury, article, view, tissue, google, scholar, pmid, pubmedncbi, control, model, months, ntx, bacl, analysis, ctx, freeze, data, scs, observed, skeletal, inflammatory, stem, process, network, mice, levels, scale, cytokines, vessel, bar, study, vascular, organisation, post, represent, significant, detected, loss, image,

Topics {✒️}

artid=1167629&tool=pmcentrez&rendertype=abstract pmid regenerative biology cookies plos plos global analysis 200 publications referring diseases dh db ab contributed reagents/materials/analysis tools dh fc gj pr st fc jak-stat signaling liquid nitrogen-cooled isopentane original author supporting information files z-stack image eighteen hours post-fi dh jmc afm-vaincre les myopathies dh ag anti-inflammatory cytokines increased pax7 ihc–fig 1b pax7-positive satellite cells liquid nitrogen rod fluorescence-activated cell sorting water ad libitum regenerative medicine 180d post-bacl2 injection pax7-expressing satellite cells sterile demineralized water decreased 1-month post-injury stem cell function internal medicine 180d post-notexin injection 180d post-cardiotoxin injection fibroblast growth factor suggesting persistent inflammation cytokine/chemokine expression profile normal 1-month post-bacl2 uninjured areas depending skeletal muscle regeneration post open skin crushed adult muscle blood borne macrophages skeletal muscle induced enhance muscle growth multifocal chronic inflammation total body mass observed 1-month post-injury rat skeletal muscle

Questions {❓}

Social Networks {👍}(3)

External Links {🔗}(259)

Analytics and Tracking {📊}

  • Facebook Pixel
  • Google Analytics
  • Google Analytics 4
  • Google Tag Manager
  • Google Universal Analytics
  • HubSpot

Libraries {📚}

  • Foundation
  • jQuery
  • Leaflet
  • Lightbox
  • Modernizr
  • Moment.js
  • Underscore.js
  • Video.js
  • Vue.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Cloudflare
  • Crossref

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