
DOI . ORG {
}
Title[redir]:
RNA aptamers selectively modulate protein recruitment to the cytoplasmic domain of β-secretase BACE1 in vitro
Description:
A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
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Keywords {🔍}
rna, bace, bonn, protein, bct, article, author, domain, binding, site, submit, aptamers, βsecretase, universität, germany, activity, ccs, gga, phosphorylation, online, copyright, society, home, subscribe, advertise, info, archive, contact, search, selectively, recruitment, cytoplasmic, michael, famulok, limes, program, unit, chemical, biology, medicinal, chemistry, βamyloid, peptide, alzheimers, disease, target, short, inhibitors, email, published,
Topics {✒️}
adp ribosylation factor-binding aptamer-binding specifically interferes casein kinase-dependent phosphorylation β-amyloid precursor protein e-mail investigate b1-ct activity β-secretase bace1 β-amyloid peptide vitro andrea rentmeister1 functional studies focusing membrane-proximal half michael famulok gerhard-domagk-strasse 1 rna aptamers single phosphorylation site short cytoplasmic tail permits gga1 association org/cgi/doi/10 article published domain-specific inhibitors β-secretase selectively target article » table 1355-8382 online issn rna inhibitors b1-ct binding site γ-secretase advance august 3 short peptide gga1 binding article bace1 resides authentic bace1 search cytoplasmic domain recruitment aβ production enzymatic activity 1261/rna 126306 rna 2006 anke bill1 tina wahle2 jochen walter2 major component disease senile plaques sequential cleavage valuable target extracellular domain
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