
DOI . ORG {
}
Title[redir]:
Mechanism of substrate selection by a highly specific CRISPR endoribonuclease
Description:
A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
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Keywords {๐}
rna, article, author, substrate, crispr, csy, online, submit, endoribonuclease, california, berkeley, rnas, copyright, society, home, subscribe, advertise, info, archive, contact, search, selection, highly, department, usa, systems, targeting, cas, crrna, interactions, date, binding, scissile, phosphate, specificity, recognition, email, published, print, open, access, citeulike, advance, full, articles, readers, issn, skip, main, page,
Topics {โ๏ธ}
substrate recognition employed substrate specificity endoribonuclease csy4 long precursor rnas target rna binding invasive genetic elements highest-affinity protein free supplemental material enable accurate selection advanced search mechanism crrna biogenesis requires org/cgi/doi/10 article published rna substrate crispr systems article ยป table substrate selection author crispr repeat crispr transcripts 1355-8382 online issn rna interactions highly sensitive advance february 16 csy4 recognizes small rnas downstream targeting article tight binding chemistry 2department crispr genomic loci enzymatically cleaved processing occurs repetitive sequence pseudomonas aeruginosa size reported mediated exclusively interactions upstream scissile phosphate remain bound helical geometry strict preference guanosine adjacent active site avoiding spurious received october 12 accepted december 20 details picked mendeley 3 readers
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