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We began analyzing https://journals.biologists.com/jcs/article-abstract/77/1/209/59593/An-epithelial-scatter-factor-released-by-embryo?redirectedFrom=fulltext, but it redirected us to https://journals.biologists.com/jcs/article-abstract/77/1/209/59593/An-epithelial-scatter-factor-released-by-embryo?redirectedFrom=fulltext. The analysis below is for the second page.

Title[redir]:
An epithelial scatter factor released by embryo fibroblasts | Journal of Cell Science | The Company of Biologists
Description:
ABSTRACT. Medium conditioned by human embryo fibroblasts breaks structural junctions between several types of epithelial cells, leading to separation and scattering of the cells. An assay developed in MDCK cells shows activity up to a dilution of at least 1 in 64, equivalent to less than 100 ng of total protein. The activity is non-dialysable, heat-labile, and sensitive to trypsin, and it is assumed to be due to one or more proteins. After addition of the factor, separation of MDCK cells begins in about 15 min and is complete in 10 h. It increases migration of MDCK cells into wounds, and causes collapse of domes. Locomotion of isolated cells is not enhanced, but cell shape is affected by local membrane movement. Under the culture conditions used the factor, or an associated protein, causes a weak inhibition of cell growth without cytotoxic activity. The scattering factor has not been purified, nor has a physiological role been identified, but it might be concerned in the mobilization of epithelial cells.

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open, cell, cells, menu, article, journal, biology, search, sign, factor, company, register, issue, mdck, activity, alert, content, contacts, epithelial, fibroblasts, icon, biologists, jcs, decision, manuscript, imaging, mitochondrial, policy, registered, skip, input, journals, science, articles, august, scatter, embryo, information, versions, share, tools, medium, conditioned, junctions, separation, scattering, protein, complete, membrane, conditions,

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open menu article research article conditioned medium cell science journal culture conditions fast-tracked decision making jcs fast-track option article information journals journal search purchase michael stoker marion perryman author google scholar crossref cambridge cb24 9lf local membrane movement guest editors ana �cell biology cell biology prokaryotic intracytoplasmic membranes mdck cells begins company limited skip embryo fibroblasts view access $30 cytotoxic activity institution sign permissions sign rights reserved company special issue manuscripts cell sci cell shape cell growth content register mdck cells epithelial cells decision letters initial decision account membrane composition colleagues provide jcs editors manuscript resolution activity isolated cells mrc5 cells assay developed

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            affiliation:Department of Pathology, Tennis Court Road, Cambridge and Imperial Cancer Research Fund, 44 Lincoln’s Inn Fields, London WC2 3AP, U.K.
            type:Person
            name:Perryman, Marion
            affiliation:Department of Pathology, Tennis Court Road, Cambridge and Imperial Cancer Research Fund, 44 Lincoln’s Inn Fields, London WC2 3AP, U.K.
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      description:ABSTRACT. Medium conditioned by human embryo fibroblasts breaks structural junctions between several types of epithelial cells, leading to separation and scattering of the cells. An assay developed in MDCK cells shows activity up to a dilution of at least 1 in 64, equivalent to less than 100 ng of total protein. The activity is non-dialysable, heat-labile, and sensitive to trypsin, and it is assumed to be due to one or more proteins. After addition of the factor, separation of MDCK cells begins in about 15 min and is complete in 10 h. It increases migration of MDCK cells into wounds, and causes collapse of domes. Locomotion of isolated cells is not enhanced, but cell shape is affected by local membrane movement. Under the culture conditions used the factor, or an associated protein, causes a weak inhibition of cell growth without cytotoxic activity. The scattering factor has not been purified, nor has a physiological role been identified, but it might be concerned in the mobilization of epithelial cells.
      pageStart:209
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      headline:An epithelial scatter factor released by embryo fibroblasts
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Person:
      name:Stoker, Michael
      affiliation:Department of Pathology, Tennis Court Road, Cambridge and Imperial Cancer Research Fund, 44 Lincoln’s Inn Fields, London WC2 3AP, U.K.
      name:Perryman, Marion
      affiliation:Department of Pathology, Tennis Court Road, Cambridge and Imperial Cancer Research Fund, 44 Lincoln’s Inn Fields, London WC2 3AP, U.K.

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