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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Social Networks
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://journals.physiology.org/doi/10.1152/physrev.00030.2014, but it redirected us to https://journals.physiology.org/doi/10.1152/physrev.00030.2014. The analysis below is for the second page.

Title[redir]:
Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality | Physiological Reviews | American Physiological Society
Description:
Obesity and type 2 diabetes are becoming increasingly prevalent worldwide, and both are associated with an increased incidence and mortality from many cancers. The metabolic abnormalities associated with type 2 diabetes develop many years before the onset of diabetes and, therefore, may be contributing to cancer risk before individuals are aware that they are at risk. Multiple factors potentially contribute to the progression of cancer in obesity and type 2 diabetes, including hyperinsulinemia and insulin-like growth factor I, hyperglycemia, dyslipidemia, adipokines and cytokines, and the gut microbiome. These metabolic changes may contribute directly or indirectly to cancer progression. Intentional weight loss may protect against cancer development, and therapies for diabetes may prove to be effective adjuvant agents in reducing cancer progression. In this review we discuss the current epidemiology, basic science, and clinical data that link obesity, diabetes, and cancer and how treating obesity and type 2 diabetes could also reduce cancer risk and improve outcomes.

Matching Content Categories {πŸ“š}

  • Health & Fitness
  • Education
  • Science

Content Management System {πŸ“}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {πŸ“ˆ}

What is the average monthly size of doi.org audience?

🌟 Strong Traffic: 100k - 200k visitors per month


Based on our best estimate, this website will receive around 100,019 visitors per month in the current month.
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How Does Doi.org Make Money? {πŸ’Έ}

We're unsure if the website is profiting.

Not every website is profit-driven; some are created to spread information or serve as an online presence. Websites can be made for many reasons. This could be one of them. Doi.org has a revenue plan, but it's either invisible or we haven't found it.

Keywords {πŸ”}

cancer, diabetes, risk, studies, insulin, increased, obesity, type, breast, growth, tumor, cells, reported, mortality, levels, cancers, found, increase, study, prostate, patients, metformin, effects, metabolic, receptor, cell, expression, circulating, factors, human, tumors, mice, including, glucose, women, incidence, cholesterol, signaling, loss, tissue, resistance, hyperinsulinemia, clinical, greater, effect, obese, progression, men, elevated, weight,

Topics {βœ’οΈ}

macrophage galactose/n-acetyl-galactosamine-specific lectin-1 high-fat/high-cholesterol diet american physiological society dominant-negative igf-ir specifically 3-hydroxy-3-methyl-glutaryl-coa primary erΞ±-positive human peroxisome proliferator-activated receptor preexisting obesity-related illnesses high-fat diet feeding /mitogen-activated protein kinase high-fat diet promotes aps website full-length leptin receptor copyright 2012 bioscientifica physiological genomics journal early-stage breast cancer aps member decreased high-density lipoprotein tumor necrosis factor-Ξ± journals quick search c-myc/vegf overexpressing journal reviews obesity increased low-density lipoprotein chronic low-grade inflammation adult insulin-sensitive tissues epithelial marker e-cadherin broad terms applied physiology journal elevated c-peptide levels germ-free mouse leads c-myc/vegf oncogenes download figuredownload powerpoint normal c-peptide levels potential anti-neoplastic effects oxygen-deprived conditions metabolism american journal erΞ±-positive breast adipose tissue related diet-induced obesity models increased intracellular cholesterol selective erΞ± modulator high-fat diet intermediate-density lipoprotein comprehensive review written beta cell compensation beta cell defect globular oligomeric complex adiponectin knockout mice stat3 signaling pathways small molecule inhibitor

Questions {❓}

  • If cholesterol is contributing to cancer growth and progression directly, then what mechanisms may contribute to this effect?
  • If obesity is associated with increased cancer incidence and mortality, then can intentional weight loss reduce the risk of cancer and cancer mortality?
  • Knowing that cancer cells avidly take up glucose and utilize this glucose for energy production and synthesis of building blocks, and that in uncontrolled diabetes circulating glucose is abundant, an appropriate question would be, does hyperglycemia provide tumor cells with more glucose and add to tumor proliferation?
  • These studies raised an important question: Why is AspB10 more mitogenic than human insulin, while other insulin analogs are not?

Social Networks {πŸ‘}(4)

External Links {πŸ”—}(1504)

Analytics and Tracking {πŸ“Š}

  • Crazy Egg
  • Google Analytics
  • Google Tag Manager
  • Google Universal Analytics
  • Hotjar
  • Snowplow

Libraries {πŸ“š}

  • Dropzone.js
  • Vue.js
  • Zoom.js

Emails and Hosting {βœ‰οΈ}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {πŸ“¦}

  • Feathr
  • Informz
  • Pbgrd
  • Scite

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