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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Social Networks
  9. External Links
  10. Analytics And Tracking
  11. Libraries
  12. Hosting Providers
  13. CDN Services

We began analyzing https://www.annualreviews.org/content/journals/10.1146/annurev.cellbio.21.022404.142018, but it redirected us to https://www.annualreviews.org/content/journals/10.1146/annurev.cellbio.21.022404.142018. The analysis below is for the second page.

Title[redir]:
SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS | Annual Reviews
Description:
Abstract The TGF-β family comprises many structurally related differentiation factors that act through a heteromeric receptor complex at the cell surface and an intracellular signal transducing Smad complex. The receptor complex consists of two type II and two type I transmembrane serine/threonine kinases. Upon phosphorylation by the receptors, Smad complexes translocate into the nucleus, where they cooperate with sequence-specific transcription factors to regulate gene expression. The vertebrate genome encodes many ligands, fewer type II and type I receptors, and only a few Smads. In contrast to the perceived simplicity of the signal transduction mechanism with few Smads, the cellular responses to TGF-β ligands are complex and context dependent. This raises the question of how the specificity of the ligand-induced signaling is achieved. We review the molecular basis for the specificity and versatility of signaling by the many ligands through this conceptually simple signal transduction mechanism.

Matching Content Categories {📚}

  • Telecommunications
  • Education
  • Video & Online Content

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 75,579,999 visitors per month in the current month.

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How Does Doi.org Make Money? {💸}

We can't see how the site brings in money.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Doi.org has a secret sauce for making money, but we can't detect it yet.

Keywords {🔍}

annual, vol, review, article, cell, tgfβ, signaling, reviews, complex, signal, type, institutional, volume, specificity, smads, receptor, ligands, transduction, contact, usage, content, login, publications, journal, subscribe, developmental, biology, versatility, publication, info, share, related, factors, smad, receptors, transcription, regulate, mechanism, cited, christopher, knowable, magazine, news, charleston, advisor, grain, copyright, cookies, track, preferencesi,

Topics {✒️}

transmembrane serine/threonine kinases tgf-β family comprises sequence-specific transcription factors annual reviews read smads xin-hua feng1 annual reviews signal transduction mechanism regulate gene expression smad complexes translocate news careers contact tgf-β receptor track usage tgf-β signaling heteromeric receptor complex receptor complex consists vertebrate genome encodes bone morphogenetic protein clotilde théry vol roel nusse vol zena werb vol submission editorial principles ligand-induced signaling wnt signaling pathway tgf-β ligands fewer type ii article preparation signal transduction preferences discover content policies contact publications a journal information higgins vol bassler vol related articles journals a grain libraries type ii cell surface cell communication understand skip perceived simplicity cellular responses context dependent molecular basis intercellular interactions graça raposo disease catriona 781–810 abc transporters man christopher

Social Networks {👍}(5)

External Links {🔗}(170)

Analytics and Tracking {📊}

  • Google Analytics
  • Google Analytics 4
  • Google Tag Manager

Libraries {📚}

  • Fancybox
  • jQuery
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Cloudflare
  • Shareaholic

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