
DOI . ORG {
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Title[redir]:
The Influence of Innate and Adaptive Immune Responses on Atherosclerosis | Annual Reviews
Description:
Both the chronic development of atherosclerotic lesions and the acute changes in lesion phenotype that lead to clinical cardiovascular events are significantly influenced by the innate and adaptive immune responses to lipoprotein deposition and oxidation in the arterial wall. The rapid pace of discovery of mechanisms of immunologic recognition, effector functions, and regulation has significantly influenced the study of atherosclerosis, and our new knowledge is beginning to affect how we treat this ubiquitous disease. In this review, we discuss recent advances in our understanding of how innate and adaptive immunity contribute to atherosclerosis, as well as therapeutic opportunities that arise from this knowledge.
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Keywords {🔍}
annual, vol, disease, article, review, mechanisms, reviews, institutional, volume, innate, adaptive, immune, atherosclerosis, contact, usage, content, login, publications, journal, subscribe, pathology, responses, publication, info, share, phenotype, clinical, cardiovascular, events, significantly, influenced, knowledge, lymphocytes, cited, cancer, impact, knowable, magazine, news, charleston, advisor, grain, copyright, cookies, track, preferencesi, understand, skip, register, cart,
Topics {✒️}
annual reviews read clinical cardiovascular events annual reviews clinical impact news careers contact track usage adaptive immune responses discuss recent advances adaptive immunity contribute pierre-yves desprez resistance sreya bagchi submission editorial principles judith campisi vol disease relevance marcia oxidation-specific epitopes cited rss feed 2014 review article preferences article preparation discover content policies contact publications a journal information disease volume 9 cardiovascular disease journals a sinclair vol engleman vol friedman vol croce vol grain libraries ubiquitous disease understand skip chronic development atherosclerotic lesions lesion phenotype significantly influenced lipoprotein deposition arterial wall rapid pace immunologic recognition effector functions therapeutic opportunities secretory phenotype dark side ana krtolica 99–118 mammalian sirtuins biological insights robert yuan michela garofalo
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