Here's how DOI.ORG makes money* and how much!

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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Social Networks
  9. External Links
  10. Analytics And Tracking
  11. Libraries
  12. Hosting Providers
  13. CDN Services

We began analyzing https://www.annualreviews.org/content/journals/10.1146/annurev-med-070909-182917, but it redirected us to https://www.annualreviews.org/content/journals/10.1146/annurev-med-070909-182917. The analysis below is for the second page.

Title[redir]:
Mechanisms of Endocrine Resistance in Breast Cancer | Annual Reviews
Description:
The estrogen receptor (ER) pathway plays a pivotal role in breast cancer development and progression. Endocrine therapy to block the ER pathway is highly effective, but its usefulness is limited by common intrinsic and acquired resistance. Multiple mechanisms responsible for endocrine resistance have been proposed and include deregulation of various components of the ER pathway itself, alterations in cell cycle and cell survival signaling molecules, and the activation of escape pathways that can provide tumors with alternative proliferative and survival stimuli. Among these, increased expression or signaling of growth factor receptor pathways, especially the EGFR/HER2 pathway, has been associated with both experimental and clinical endocrine therapy resistance. New treatment combinations targeting both ER and growth factor receptor signaling to block the crosstalk between these pathways and eliminate escape routes have been proven highly effective in preclinical models. Results of recent clinical studies, while partly supporting this approach, also highlight the need to better identify a priori the patients whose tumors are most likely to benefit from these specific cotargeting strategies.

Matching Content Categories {📚}

  • Science
  • Health & Fitness
  • Education

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 91,205,781 visitors per month in the current month.

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How Does Doi.org Make Money? {💸}

We're unsure if the website is profiting.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Doi.org might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

annual, vol, article, endocrine, resistance, receptor, review, mechanisms, cancer, reviews, pathway, therapy, signaling, factor, institutional, volume, pathways, growth, contact, usage, content, login, publications, journal, subscribe, medicine, breast, publication, info, share, estrogen, block, highly, effective, cell, survival, escape, tumors, clinical, crosstalk, cited, berger, knowable, magazine, news, charleston, advisor, grain, copyright, cookies,

Topics {✒️}

annual reviews read annual reviews news careers contact recent clinical studies track usage treatment combinations targeting specific cotargeting strategies ppars joel berger serotonin miles berger cancer ramiro garzon submission editorial principles breast cancer development eliminate escape routes egfr/her2 pathway multiple mechanisms responsible proven highly effective cited rss feed article preparation preferences discover content breast cancer policies contact estrogen receptor endocrine resistance publications a journal information highly effective cell cycle survival stimuli endocrine therapy escape pathways acquired resistance medicine volume 62 journals a combination therapy moller vol gottesman vol vollset vol roth vol croce vol grain libraries pathway plays understand skip kent osborne1 1146/annurev-med-070909-182917 pivotal role common intrinsic include deregulation alternative proliferative increased expression

External Links {🔗}(177)

Analytics and Tracking {📊}

  • Google Analytics
  • Google Analytics 4
  • Google Tag Manager

Libraries {📚}

  • Fancybox
  • jQuery
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Cloudflare
  • Shareaholic

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