
DOI . ORG {
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Title[redir]:
CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients | Science Translational Medicine
Description:
Regulatory T cells (Tregs) are key mediators of immune tolerance and feature prominently in cancer. Depletion of CD25+ FoxP3+ Tregs in vivo may promote T cell cancer immunosurveillance, but no stra...
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science, crossref, cancer, web, pubmed, google, scholar, medicine, cells, usa, university, pennsylvania, school, philadelphia, regulatory, cell, daclizumab, view, patients, tregs, abramson, author, articles, research, article, immunity, news, tumor, department, access, immune, family, immunotherapy, vonderheide, authors, immunol, rhv, center, antibody, foxp, aaas, institute, antitumor, autoimmunity, human, fig, rech, information, function, breast,
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reviewers librarians manage telomerase-specific t-cell immunity cell subset analysis drug administration–approved antibody authors information adoptive t-cell transfer full text partner authors affiliations andrew late-stage ovarian cancer science family account quantify cell-mediated cytolysis science google scholar social media facebook journals vaccine antigen-specific effector functional analysis cd8+ virus-specific cytotoxic il-2rα-targeted therapy insidious—inhibiting immune responses authors contributed equally member current issue il-2rβ-deficient mice anti-cd25 antibody daclizumab science news check access scholarly commentary abramson cancer center mediate antibody-dependent science family regulatory cell-mediated suppression attenuate tumor growth cancer research communications contents advertisement sign rapamycin differentially affect permissions toc alerts 33 mb references monoclonal antibody blockade cd25high cd45raneg tregs latest news il-2 receptor α citation information anti-cancer agents nih grant ca111377 commentary humanized anti-cd25 faqs access lymphoid cell lines t-cell immunity resources file
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