
DOI . ORG {
}
Title[redir]:
Programmed necrosis in inflammation: Toward identification of the effector molecules | Science
Description:
The routes to cell death are many, and distinguishing which path a particular cell may have taken remains a challenge. Wallach et al. review current understanding of how programmed necrotic cell death contributes to ...
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Keywords {🔍}
science, crossref, web, google, scholar, pubmed, cell, death, necrosis, wang, kinase, necroptosis, programmed, inflammation, protein, apoptosis, mlkl, pyroptosis, necrotic, article, signaling, rip, chen, zhang, news, access, cells, caspase, caspases, immunol, nature, wallach, view, ripk, biol, membrane, activation, aaas, nat, rev, issue, molecules, mechanisms, liu, kang, information, molecular, pathways, mixed, lineage,
Topics {✒️}
shutting tnfr-1/ripk1/ripk3/mlkl cascade pparγ/pgc-1α/tfam axis research careers compare reviewers librarians manage rip1-rip3-drp1 signaling pathway authors information receptor-interacting protein kinase–1 n-terminal proteolytic fragment inflammatory cytokines interleukin-1β full text access review share advances medicine dai/zbp1/dlm-1 complexes partner tlr4/nf-κb pathway rip3/mlkl-dependent necrosis social media facebook member current issue differing cell-death processes science google scholar latest news receptor 3-mediated necrosis journals review current understanding home science vol scholarly commentary activate cytokines il-1β science news nf-κb signaling contents advertisement sign interleukin-1β secretion institution references molecular immunology permissions toc alerts lipid metabolic pathways identifying death-effector molecules tnf-induced necrosis signaling pathways leading science family account citation information tae-bong kang pathogen component lipopolysaccharide innate immune receptors commentary check access specific cellular target cgas‐sting pathway' helix bundle domain caspase-1-induced pyroptosis
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- What are the parameters that can reliably allow us to define a cause-effect relationship between necrotic death and inflammation—and more generally, to define the causal relationships between any disease and its co-occurring pathogenic events?
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