
DOI . ORG {
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Title[redir]:
Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine | Science
Description:
Mouse primordial germ cells (PGCs) undergo sequential epigenetic changes and genome-wide DNA demethylation to reset the epigenome for totipotency. Here, we demonstrate that erasure of CpG methylati...
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Keywords {π}
science, crossref, cambridge, pubmed, web, google, scholar, cell, dna, epigenetic, article, university, germ, mouse, wellcome, research, news, institute, view, demethylation, access, development, methylation, cells, reprogramming, tet, aaas, dynamics, hydroxymethylcytosine, stem, articles, issue, erasure, information, mechanisms, primordial, free, trustcancer, gurdon, author, germline, hackett, authors, conversion, service, full, trustmedical, council, citation, jul,
Topics {βοΈ}
reviewers librarians manage science advances authors information access report share authors affiliations jamie mll partner tet1 authors contributed equally melvin khee-shing leow social media facebook wellcome trust full text genome-wide dna demethylation pluripotent stem cells transcriptome analysis primordial germ cells journals home science vol check access science news scholarly commentary mouse germ line roopsha sengupta kazuhiro murakami caroline lee author notes promoter dna methylation science family account member current issue partner undergo sequential epigenetic mouse es cells germ cell lineage latestΒ news pubmed google scholar citation information request permissions acknowledgments contents advertisement sign commentary permissions toc alerts genome-wide reprogramming single issue reprints cell mass specification somatic cell lineages embedded figures loci escape demethylation genome-wide erasure faqs access tet3 dna dioxygenase thymine dna glycosylase active dna demethylation
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