DOI . ORG {
}
We began analyzing https://www.science.org/doi/10.1126/science.1252230, but it redirected us to https://www.science.org/doi/10.1126/science.1252230. The analysis below is for the second page.
Title[redir]:
Cancer Suppression by the Chromosome Custodians, BRCA1 and BRCA2 | Science
Description:
Germline mutations in BRCA1 and BRCA2 predispose to common human malignancies, most notably tumors of the breast and ovaries. The proteins encoded by these genes have been implicated in a plethora of biochemical interactions and biological functions, ...
Title[redir]:
Cancer Suppression by the Chromosome Custodians, BRCA1 and BRCA2 | Science
Description:
Germline mutations in BRCA1 and BRCA2 predispose to common human malignancies, most notably tumors of the breast and ovaries. The proteins encoded by these genes have been implicated in a plethora of biochemical interactions and biological functions, ...
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Keywords {🔍}
science, crossref, brca, pubmed, web, google, scholar, cancer, cell, dna, breast, venkitaraman, lee, mutation, chen, repair, nat, mol, tumor, biol, news, human, rad, nature, natl, protein, access, article, cells, proc, acad, sci, usa, response, recombination, mutations, aaas, livingston, ovarian, issue, suppression, genes, gene, suppressor, ashworth, genet, van, tutt, information, susceptibility,
Topics {✒️}
regulates cep55 signaling atm/brca1-dependent dna methylation reviewers librarians manage rpa-covered single-stranded dna authors information experimental medicine ring heterodimer brca1-bard1 authors affiliations ashok double-strand dna breaks icgc mmml-seq consortium member current issue hrad50-hmre11-p95 complex articles recurrent high-grade serous moroccan retrospective analysis full text nuclear partner social media facebook dna-damage selective role brca1-positive breast cancers journals triple-negative breast cancer breast cancer-derived mutation resection-mediated dna repair risk-reducing salpingo-oophorectomy real-world outcomes spindle assembly checkpoint wild-type brca allele tissue-specific tumor development protein-protein interaction networks brca2 germline mutations brca-mutated breast cancers homology-directed repair science google scholar scholarly commentary brca2-dss1-ssdna structure check access home science vol brca2 mediate structural human somatic cells dna damage response dna-damage response heterochromatin-mediated silencing view options log single-stranded dna prospective analysis integrated analysis science news inactivation promotes carcinogenesis ubiquitin ligase inactivated
Questions {❓}
- , Characterization of segments from the central region of BRCA1: An intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?
- ALREADY A SUBSCRIBER OR AAAS MEMBER?
- Should grant applicants judge competitors’ proposals?
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