
DOI . ORG {
}
Title[redir]:
FBXW7 Targets mTOR for Degradation and Cooperates with PTEN in Tumor Suppression | Science
Description:
The enzyme mTOR (mammalian target of rapamycin) is a major target for therapeutic intervention to treat many human diseases, including cancer, but very little is known about the processes that control levels of mTOR protein. Here, we show that ...
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science, crossref, cancer, google, scholar, web, pubmed, san, francisco, article, view, news, fbxw, access, mtor, cell, aaas, usa, university, california, research, articles, issue, information, free, institute, sutter, street, author, journals, degradation, tumor, service, full, citation, jun, careers, share, authors, options, eletters, text, scienceinsider, advertisement, commentary, log, targets, pten, notes, figures,
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org/cgi/content/full/321/5895/1499/dc1 materials research careers compare reviewers librarians manage authors information cancer research institute access reports share member current issue full text diana marisol abrego-guandique partner home science vol hio chung kang vector encoding ha-ubiquitin jian-hua mao science news il-jin kim social media facebook latestΒ news journals science family account scholarly commentary contents advertisement sign permissions toc alerts author notes β check access single issue reprints amino acid residues inspire multispectral materials commentary citation information cancer drug targets5 improving cancer immunotherapy science family view options log 96 kb references faqs access embedded figures colorectal cancer patients cell receptor profiling science volume 321 science faq science donate science issn 0036-8075 aaas member activate release papers archive primary tumors showed dld1 wild-type de-fg02-03er63630 submission history received kras mutational status
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