
DOI . ORG {
}
Title[redir]:
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome
Description:
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
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Keywords {๐}
breakpoints, genome, medicine, article, baylor, college, houston, texas, usa, cancer, online, author, mcf, breast, cell, laboratory, submit, chromosomal, research, center, total, distinct, dispersed, lcrs, genes, expressed, copyright, cold, spring, harbor, press, grv, readers, page, home, archive, subscribe, advertise, info, contact, search, sequencelevel, map, line, human, sequencing, department, molecular, somatic, clustered,
Topics {โ๏ธ}
double-stranded dna breaks plate/row/column names combines end-sequence profiling increased anchorage-independent growth duncan cancer center mcf-7 bac clones homology-driven repair cancer genome oliver massively parallel sequencing nonhomologous end-joining expressed fusion products sequence-level map petra den hollander4 low copy repeats array cgh located protein complexes responsible including increased proliferation short read archives article published online closely spaced breakpoints highly amplified regions free supplemental material 4 breast center involve genes coding ncbi trace cell growth 1088-9051 online issn org/cgi/doi/10 mcf-7 detected article published cell lines author article ยป table advance december 3 ncbi human genetics [supplemental material sequence data issue alert 108 genome res including 10 fusions coding exons distinct types distinct clusters chromosomal breakpoints jian li1 cristian coarfa1 stephen richards2 aleksandar milosavljevic1 baylor college
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