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Title[redir]:
The American Journal of Surgical Pathology
Description:
EGFR mutations and identified 10 adenocarcinomas with BRAF-V600E mutation. All BRAF-V600E mutations were heterozygous. There was a slight female predilection (6:4) in these elderly patients (average age 67 y) who were found to have a greater than expected incidence of intralobar satellite nodules and N2 node involvement. The adenocarcinomas were largely of mixed type with a high incidence of papillary (80%) and lepidic growth (50%). Adenocarcinomas with this clinicopathologic phenotype may be worthwhile investigating for BRAF-V600E mutation as more genetically oriented drug therapies emerge....
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Keywords {🔍}
journal, adenocarcinomas, issue, mutations, access, subscribe, alerts, articles, authors, abstract, lung, brafve, log, register, logo, issues, adenocarcinoma, buy, braf, kras, egfr, phenotype, mutation, incidence, text, subscribers, request, browse, content, submit, service, privacy, policy, secondary, advanced, search, info, previous, original, histopathology, brafvemutated, yousem, samuel, nikiforova, marina, nikiforov, yuri, phd, author, information,
Topics {✒️}
braf-v600e mutations braf-v600e mutation journal authors submit full text access mutually exclusive mutations slight female predilection intralobar satellite nodules n2 node involvement artificial intelligence training lung lacking kras etoc alerts lung adenocarcinoma service request 800-638-3030 register subscribe individual subscribers log american journal journal tables issue braf adenocarcinomas egfr mutations website subscribe journal center submit surgical pathology 32 frequently reported egfr genes histologic phenotype elderly patients average age 67 expected incidence mixed type high incidence lepidic growth clinicopathologic phenotype worthwhile investigating email inbox rights reserved data mining marina md yuri md analyzed 222 adenocarcinomas identified 10 adenocarcinomas authors content log kras subscribers text md adenocarcinomas
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