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Title[redir]:
Current Opinion in Nephrology and Hypertension
Description:
role of vitamin D in host defense against infection. Recent findings This review will consider two examples of vitamin D-regulated innate immunity that have been recently explored: the role of vitamin D signaling within macrophages to enable them to respond to and kill Mycobacterium tuberculosis organisms, and the role of vitamin D signaling in the keratinocytes of the epidermis to enable them to respond to disruption of their barrier function. Potential application to periodontal disease will then be considered. Summary Both adaptive and innate immune processes are two edged: beneficial and harmful. Although suppression of adaptive immunity may be beneficial in a number of self-destructive diseases, such suppression may predispose to infection. Enhancement of innate immunity is clearly beneficial in diseases like tuberculosis, but potentiation of proinflammatory processes can increase tissue destruction as in bone loss in periodontal disease. The balance, however, favors adequate vitamin D nutrition in host defense against infection....
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Keywords {🔍}
vitamin, journal, role, issue, infection, immunity, innate, access, subscribe, alerts, authors, abstract, immune, review, adaptive, signaling, beneficial, log, register, logo, articles, issues, current, buy, function, host, defense, enable, respond, tuberculosis, periodontal, disease, processes, suppression, diseases, text, subscribers, request, browse, content, submit, service, privacy, policy, secondary, advanced, search, info, previous, mineral,
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journal authors submit full text access regulating calcium homeostasis increase tissue destruction artificial intelligence training etoc alerts favors adequate vitamin innate immune processes service request 800-638-3030 register subscribe individual subscribers log journal tables issue innate immunity website subscribe journal proinflammatory processes center submit immune system immune function justin silver host defense recent findings recently explored barrier function potential application periodontal disease bone loss email inbox rights reserved data mining adaptive immunity bushinsky vitamin destructive diseases authors content innate immunity tuberculosis log subscribers text vitamin infection diseases adaptive edited david role protection
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