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Title[redir]:
American Journal of Therapeutics
Description:
sm. The peroxisome proliferator-activated receptors have been identified as key regulators of glucose and lipid metabolism, because they act as transcription factors that stimulate protein synthesis in a wide variety of processes (energetic metabolism, proliferation, and cellular differentiation), of which have been identified 3 types (α, β/δ, γ). The thiazolidenediones are compounds that act as agonists of the peroxisome proliferator-activated receptor-γ increasing the tissues sensibility (muscle, adiposity tissue, and liver) to the insulin action; that is why they are used nowadays in treatment of type 2 diabetes mellitus. These drugs produce several of adverse effects, such as weight increased, edema, anemia, pulmonary edema, and congestive cardiac failure. Even their use have been related for some studies to an increased in the myocardium infarct risk; this correlation has not been a strong determinant to remove them from the market....
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Keywords {🔍}
journal, bsc, issue, access, subscribe, alerts, authors, abstract, type, diabetes, mellitus, insulin, metabolism, log, register, logo, articles, issues, agonists, phd, parra, buy, protein, peroxisome, proliferatoractivated, identified, act, increased, edema, text, subscribers, request, browse, content, submit, service, privacy, policy, secondary, advanced, search, info, previous, lash, symposium, pparγ, role, management, bermúdez, valmore,
Topics {✒️}
peroxisome proliferator-activated receptors frequent endocrine-metabolic diseases journal authors submit full text access congestive cardiac failure myocardium infarct risk artificial intelligence training stimulate protein synthesis insulin secretion defects etoc alerts service request 800-638-3030 register subscribe individual subscribers log journal tables issue journal website subscribe protein metabolism center submit insulin resistance insulin action abstract valmore md freddy bsc1 nailyn bsc1 maria bsc1 adriana bsc1 lianny bsc1 daviel bsc1 joselyn md1 nailet msc manuel md pathogenic basis key regulators lipid metabolism transcription factors wide variety energetic metabolism cellular differentiation β/δ γ tissues sensibility adiposity tissue drugs produce adverse effects strong determinant email inbox rights reserved data mining identified 3 types
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