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DOI . ORG {}

Detected CMS Systems:

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
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We began analyzing https://journals.lww.com/immunotherapy-journal/abstract/2010/01000/increased_intensity_lymphodepletion_enhances_tumor.1.aspx, but it redirected us to https://journals.lww.com/immunotherapy-journal/abstract/2010/01000/increased_intensity_lymphodepletion_enhances_tumor.1.aspx. The analysis below is for the second page.

Title[redir]:
Journal of Immunotherapy
Description:
hat high-dose total body irradiation given together with hematopoietic stem cell (HSC) transplantation effectively enhances ACT, the relationship between the intensity of lymphodepletion and tumor treatment efficacy has not been systematically studied. Using the pmel-1 mouse model of self/tumor-reactive CD8+ T cells, we observed a strong correlation between the intensity of the conditioning regimen and the efficacy of ACT-based treatments using linear regression analysis. This was the case for preparative total body irradiation administered either as a single dose (R2=0.97, P<0.001) or in fractionated doses (R2=0.94, P<0.001). Increased amounts of preparative total body irradiation were directly correlated with progressively more favorable ratios of transferred tumor-reactive CD8+ T cells toward endogenous cells with the potential for inhibitory activity including: CD4+ cells (potentially T regulatory cells); Gr1+ cells (which are capable of functioning as myeloid-derived suppressor cells); and endogenous CD8+ and natural killer 1.1+ cells (that can act as “sinks” for homeostatic cytokines in the postablative setting). With increasing ablation, we also observed elevated lipopolysaccharide levels in the sera and heightened levels of systemic inflammatory cytokines. Thus, increased intensity lymphodepletion triggers enhanced tumor treatment efficacy and the benefits of high-dose total body irradiation must be titrated against its risks....

Matching Content Categories {📚}

  • Science
  • Health & Fitness
  • Books & Literature

Content Management System {📝}

What CMS is doi.org built with?


Doi.org utilizes MYBB.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌍 Impressive Traffic: 500k - 1M visitors per month


Based on our best estimate, this website will receive around 600,019 visitors per month in the current month.
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How Does Doi.org Make Money? {💸}

We see no obvious way the site makes money.

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Keywords {🔍}

cells, journal, access, issue, intensity, lymphodepletion, efficacy, total, body, irradiation, subscribe, alerts, authors, increased, tumor, treatment, cytokines, log, register, logo, articles, issues, rosenberg, abstract, enhances, transferred, buy, cell, actbased, increasing, homeostatic, regulatory, myeloidderived, suppressor, highdose, act, observed, preparative, endogenous, levels, text, subscribers, request, browse, content, submit, service, privacy, policy, secondary,

Topics {✒️}

tumor treatment efficacy adoptively transferred tumor-specific enhance anti-tumor responses transferred tumor-reactive cd8+ myeloid-derived suppressor cells /tumor-reactive cd8+ author information journal full text access adoptive cell transfer augmenting innate immunity hematopoietic stem cell pmel-1 mouse model linear regression analysis inhibitory activity including artificial intelligence training journal authors submit increased amounts systemic inflammatory cytokines etoc alerts act-based treatments service request 800-638-3030 register subscribe individual subscribers log journal tables increasing access lymphodepletion single dose issue efficacy intensity endogenous cd8+ heightened levels website subscribe journal based immunotherapies center submit homeostatic cytokines cells wrzesinski systematically studied strong correlation conditioning regimen fractionated doses directly correlated favorable ratios endogenous cells cd4+ cells gr1+ cells natural killer 1 postablative setting increasing ablation

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Analytics and Tracking {📊}

  • Comscore
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Libraries {📚}

  • Bootstrap
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Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
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Name Servers:

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CDN Services {📦}

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