
DOI . ORG {
}
Title[redir]:
Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization | PNAS
Description:
We isolated hematopoietic stem cells (HSC) from mice treated with cyclophosphamide (CY) and granulocyte colony-stimulating factor (G-CSF). All mobilized multipotent progenitor activity was containe...
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Keywords {🔍}
cells, mice, maccdckit, marrow, hsc, bone, blood, progenitors, google, scholar, crossref, pubmed, mobilized, day, populations, spleen, maclocd, multipotent, cell, progenitor, treatment, number, reconstituted, activity, cygcsf, normal, ltmr, gcsf, cygcsftreated, spleens, mobilization, longterm, days, irradiated, population, donor, splenic, hematopoietic, recipients, single, observed, reconstitution, table, colonies, numbers, weissman, cycle, frequency, injected, wbm,
Topics {✒️}
cy/g-csf mobilized thy-1losca-1+lin−mac-1−cd4−c-kit+ 1+sca-1+lin−mac-1lo cd4−c-kit+ cells thy-1losca-1+lin−mac-1−cd4−c-kit+ 1losca-1+lin−mac-1−cd4−c-kit+ cells 1losca-1+lin−mac-1−cd4−c-kit+ hsc 1+sca-1+lin−mac-1−cd4−c-kit+ 1+sca-1+lin−mac-1+cd4−c-kit+ mac-1−cd4−c-kit+ cells noted mobilized splenic mac-1−cd4−c-kit+ thy-1losca-1+lin−mac-1locd4− cells mac-1−cd4−c-kit+ cell levels mac-1−cd4−c-kit+ cells appeared mobilized mac-1−cd4−c-kit+ cells mac-1−cd4−c-kit+ cells isolated single mac-1−cd4−c-kit+ cells mac-1−cd4−c-kit+ cell numbers 1losca-1+lin−/loc-kit+ cells mac-1−cd4−c-kit+ cell frequency splenic mac-1−cd4−c-kit+ 23 splenic mac-1−cd4−c-kit+ granulocyte colony-stimulating factor thy-1losca-1+lin−mac-1locd4− 1losca-1+lin−mac-1locd4− cells mobilized mac-1−cd4−c-kit+ mac-1−cd4−c-kit+ cells single mac-1−cd4−c-kit+ mac-1−cd4−c-kit+ population cy/g-csf-treated mice antigen cy/g-csf treatment induces 1losca-1+lin−/lo subpopulation mac-1−cd4−c-kit+ cy/g-csf treatment drove cy/g-csf-treated mice phycoerythrin-conjugated anti-rat antibody cy/g-csf treatment thy-1 cy/g-csf treatment caused reduced c-kit expression splenic mac-1locd4− cells long-term progenitor content anti-c-kit antibody long-term multilineage reconstituting steel factor acknowledgments streptavidin-conjugated magnetic beads social media facebook retro-orbital venous sinus jan-willem van ittersum cy/g-csf treatment long-term reconstituting hsc x-ray machine operated colony forming unit-spleen
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