
DOI . ORG {
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Title[redir]:
Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients | PNAS
Description:
Preoperative bevacizumab and chemotherapy may benefit a subset of breast cancer (BC) patients. To explore potential mechanisms of this benefit, we conducted a phase II study of neoadjuvant bevacizu...
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Keywords {🔍}
patients, bevacizumab, cancer, tumor, response, mvd, google, scholar, pubmed, crossref, vessels, tnbc, therapy, baseline, hrbc, vascular, breast, table, vessel, pcmvd, fig, chemotherapy, increased, regression, fraction, neoadjuvant, biomarkers, medical, normalization, sciences, treatment, department, high, study, articles, biomarker, values, view, pathologic, pcr, postbevacizumab, data, increase, tumors, analysis, boston, scores, school, functional, harvard,
Topics {✒️}
social media facebookx cochran–mantel–haenszel χ2 tests abstract preoperative bevacizumab tables s4–s6 dana–farber cancer institute depth science stories odds ratios significance jan-willem van ittersum discussion bc computational biology potential mechanistic link paraffin-embedded tissue blocks kruskal–wallis ranked tests anti-vegf therapy-induced pruning detectable residual disease—referred copy copied pericyte-covered vessel perimeter triple-negative breast cancer nonsmall-cell lung cancer pam50 gene signature mathematical physics pericyte-covered compressed vessels sciences vol hormone receptor-positive bc prognostic significance growth-induced solid stress cerebral blood volume quick search longer disease-free survival increased pericyte-covered mvd her2-negative breast cancer authors affiliations sara gene expression profile si methods patients care dose-dense chemotherapy increased pc-mvd correlating sophisticated auditory–motor learning pericyte-covered patent vessels αsma-positive perivascular cells locally advanced carcinoma low/intermediate grade tumor triple-negative carcinoma patients dose-dense acp chemotherapy received research grants microvessel metrics chemotherapy-induced tumor regression journals enter journal acknowledgments lymph node metastases librarian recommend pnas
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- F Andre, E Deluche, H Bonnefoi, Bevacizumab: The phoenix of breast oncology?
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- GW Sledge, Anti-vascular endothelial growth factor therapy in breast cancer: Game over?
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