
DOI . ORG {
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Title[redir]:
Regulation of NF-κB activity through lysine monomethylation of p65 | PNAS
Description:
NF-κB is a key activator of inflammatory and immune responses with important pathological roles in cancer, heart disease, and autoimmune diseases. Transcriptional activity of NF-κB is regulated by ...
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Keywords {🔍}
set, methylation, tnfα, cells, fig, nfκb, nuclear, crossref, pubmed, google, scholar, expression, stimulation, lysine, genes, iκbα, activity, shown, extracts, control, response, histone, induction, hek, antibodies, cell, proteins, antibody, pkme, article, regulated, treated, results, information, methylated, regulates, required, subset, transfected, regulation, methyltransferase, promoter, binding, activation, dnap, cytoplasmic, vitro, sirnas, function, authors,
Topics {✒️}
/pan-methyl-lysine-methyl-k-pan-antibody-chip-grade-ab7315 org/cgi/content/full/0910439106/dcsupplemental ikappab-nf-kappab signaling module nf-κb-driven luciferase reporter nf-kappa b-dependent transcription subset nf-κb-dependent gene nf-kappab-dependent inflammatory genes subset nf-κb-regulated genes social media facebook figures represent data nf-kappab signaling pathways p65 chee-kwee ea nf-κb-dependent genes n-terminal gst tag nf-κb-depedent genes jan-willem van ittersum retinoic acid receptor-alpha supporting information online tumor necrosis factor-α post-translational modifications regulating nf-κb target genes nf-κb-regulated genes nf-κb regulated genes manage alerts nf-κb nf-κb family members national academy nf-κb family proteins tnf-treated set9-deficient cells protein microarray-based analysis wild-type p65 led current emotional state stable dna-p65 complexes supporting information stable dna-p65 interactions il-1β treatment led detect wild-type p65 sophisticated auditory–motor learning methylated-lysine-specific antibody set9-mediated p65-k37 methylation gst–p65 fusion proteins nf-κb represents allowing nf-κb librarian recommend pnas methylated-lysine binding domains nf-κb activation tnfα-treated human monocytes gst-induced dimerization nf-kappab complexes methylated-lysine-specific antibodies tnf induced degradation
Questions {❓}
- R Margueron, P Trojer, D Reinberg, The key to development: Interpreting the histone code?
- What is the mechanism for methylation-induced stabilization of DNA-p65 complexes?
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