
DOI . ORG {
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Title[redir]:
Enhanced selection of FoxP3+ T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease | PNAS
Description:
It is generally acknowledged that cytotoxic T-lymphocyte–associated antigen-4 (CTLA-4/CD152) plays a pivotal role in the regulation of T-cell activation and the establishment of self-tolerance in t...
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Keywords {🔍}
cells, mice, foxp, ctla, treg, cdcd, crossref, pubmed, google, scholar, sciences, thymus, disease, expression, cell, fig, role, peptide, tgragctla, antigen, mbp, article, selection, eae, research, autoimmune, activation, spontaneous, thymic, immunol, medical, ctlako, function, tcr, data, anticd, bristol, regulatory, articles, specific, higher, vitro, helical, authors, information, development, enhanced, view, tcell, shown,
Topics {✒️}
social media facebookx fab2′ donkey anti-rat-rhodamine org/cgi/content/full/0803186106/dcsupplemental perkin-elmer life sciences standard fmoc chemistry liquid scintillation β-counter greater steady-state turnover jan-willem van ittersum foxp3+ treg-cell population cd4+cd25+foxp3+ treg cells b7–1/b7–2/ctla-4 ko mice steady-state cd4+ foxp3+ supporting information online acetylated n-terminal peptide affinity-purified anti-cd3e 1 μg/ml anti-cd3 t-cell proliferation assays neutralizing anti-ctla-4 antibodies plate-bound anti-cd3e specific pathogen-free conditions copy copied depth science stories blocking anti-cd28 mab affinity-purified anti-foxp3 current emotional state foxp3+ cd4cd8 double-positive guest editor invited mathematical physics disproportionate t-cell activation tg4 ko cd4+cd25− myelin basic protein editorial board anti-ctla-4–treated mice do11+rag2−/−ctla-4−/− mice medical research council quick search anti-cd28 mab revealed steady-state expansion cd4-depleted tg4 splenocytes experimental autoimmune encephalomyelitis nontransgenic ctla-4ko models t-cell receptor cd4+cd25+ treg cells tg4 wt cd4+cd25− sophisticated auditory–motor learning results ctla-4ko mice general lymphoproliferative disease medical sciences augmented treg-cell numbers journals enter journal
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