DOI . ORG {
}
We began analyzing https://pnas.org/doi/full/10.1073/pnas.0704652104, but it redirected us to https://pnas.org/doi/full/10.1073/pnas.0704652104. The analysis below is for the second page.
Title[redir]:
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer | PNAS
Description:
Colon cancer has been viewed as the result of progressive accumulation of genetic and epigenetic abnormalities. However, this view does not fully reflect the molecular heterogeneity of the disease....
Title[redir]:
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer | PNAS
Description:
Colon cancer has been viewed as the result of progressive accumulation of genetic and epigenetic abnormalities. However, this view does not fully reflect the molecular heterogeneity of the disease....
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Keywords {🔍}
cimp, methylation, genes, genetic, cancer, epigenetic, cases, pubmed, groups, google, scholar, analysis, crossref, markers, distinct, group, mutation, mutations, colon, view, kras, issa, braf, clustering, cancers, negative, fig, predictive, data, articles, clinical, table, mint, cluster, article, cimpnegative, based, author, patients, crc, clusters, higher, pdf, research, subclasses, information, analyzed, alterations, cpg, colorectal,
Topics {✒️}
org/cgi/content/full/0704652104/dc1 supporting information online social media facebook promote tumor development single-strand conformational polymorphism supporting information k-means clustering analyses jan-willem van ittersum k-means clustering analysis perform k-means clustering adjacent normal-appearing tissues cpg-rich region called cancer-specific mint markers average methylation z-score pnas direct submission sophisticated auditory–motor learning k-means clustering anderson cancer center jp issa including tumor-suppressor genes authors declare targeting age-related genes promote colon cancer transcription start site share librarian recommend pnas current classifications based cimp-positive cases fit jpj issa unsupervised hierarchical clustering average z-scores pnas highlights newsletter national academy colon cancer consists colon cancer proceedings citation information current emotional state significantly higher incidence previous cimp-negative group related individual variability proximal colon cancer epigenetic information normal-appearing mucosa fundamental building blocks respective z-scores colorectal cancer groups primary colorectal cancers carnegie mellon university hierarchical clustering results previous hierarchical clustering
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