
DOI . ORG {
}
Title[redir]:
CD98hc (SLC3A2) mediates integrin signaling | PNAS
Description:
Integrins regulate cellular behaviors through signaling pathways, including Rho GTPases and kinases. CD98 heterodimers, comprised of a heavy chain (CD98hc, SLC3A2) and one of several light chains, ...
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Keywords {🔍}
cdhc, cells, cell, fig, integrins, google, scholar, crossref, rac, pubmed, activation, integrin, signaling, reconstituted, spreading, akt, phosphorylation, research, domain, min, biol, fibroblasts, integrindependent, migration, null, data, tumors, article, pathways, binding, department, jolla, transmembrane, clone, flow, adhesion, fak, tumor, mediates, view, growth, required, mice, protein, pnas, expression, anoikis, cytometry, similar, cte,
Topics {✒️}
cellular behaviors leading authors affiliations chloe pi3-kinase inhibitor wortmannin integrin-coupled c98t98e69-protected cells cellular behaviors supporting information sds/page sample buffer cas/crk/dock180 complex 20 mm tris·hcl mediates integrin-dependent signals similar dose–response curve notes author contributions jan-willem van ittersum amino acid transport platelet-derived growth factor pi3-kinase downstream target efficient adhesion-induced activation higher-power images revealed rac v12-expressing cells restored integrin-dependent signaling homozygous cd98hc-deficient clones 4/150 mm nacl/1 protease inhibitors anchorage deprivation-induced apoptosis anchorage-dependent survival signals examined integrin-dependent haptotaxis multiple cellular lineages infecting cd98hc-deficient cells /2 mm l-glutamine integrin-dependent signals involved current emotional state soluble cell-binding domain social media facebook human cd98hc-reconstituted null author notes ‡ integrin-regulated signaling pathways integrin-dependent cell spreading discussion pi3-kinase-induced activation amino acid transporters adhesion-dependent rac activation anchorage-independent cell growth cd98hc-deficient es cells adhesion-dependent cell migration sophisticated auditory–motor learning rescued integrin-dependent signaling nuclear dye yopro-1 serum-free dmem acknowledgments glass coverslips coated
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