DOI . ORG {
}
We began analyzing https://pnas.org/doi/full/10.1073/pnas.98.1.87, but it redirected us to https://pnas.org/doi/full/10.1073/pnas.98.1.87. The analysis below is for the second page.
Title[redir]:
Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin | PNAS
Description:
Trichostatin A (TSA) and trapoxin (TPX) are potent inhibitors of histone deacetylases (HDACs). TSA is proposed to block the catalytic reaction by chelating a zinc ion in the active-site pocket thro...
Title[redir]:
Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin | PNAS
Description:
Trichostatin A (TSA) and trapoxin (TPX) are potent inhibitors of histone deacetylases (HDACs). TSA is proposed to block the catalytic reaction by chelating a zinc ion in the active-site pocket thro...
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Keywords {🔍}
hdac, chap, tpx, google, scholar, crossref, pubmed, japan, tsa, cyclic, acid, tetrapeptide, enzyme, chaps, science, research, group, histone, inhibition, activity, cell, cells, technology, hydroxamic, concentrations, inhibitor, biotechnology, inhibitors, expression, fig, epoxyketone, chain, acetylation, corporation, tokyo, results, hdacs, showed, department, article, potent, pocket, core, shown, biol, saitama, acetylated, compounds, treated, antibiotics,
Topics {✒️}
d-pro-ala-d-ala lys-phe-phe-d-pro aoe-phe-phe-d-pro asu-phe-phe-d-pro anti-human p21waf1/cip1 antibody aoe-phe-phe-d-pip aoe-aib-phe-d-pro acid/urea/triton notes social media facebook phe-phe-d-pro conserved charge-relay histidines b16/bl6 melanoma cells phe-phe-d-pip aib-phe-d-pro d-phe-leu-pip acid/urea/triton gel electrophoresis repress mef2a-dependent transcription jan-willem van ittersum short-chain fatty acids independent dose–response curves independent dose-response curves [3h]acetyl-labeled histones isoform-specific inhibitors based references 1 anti-flag m2 antibody national academy abbreviations aoe drug-free hd buffer current emotional state 1 abstract materials author notes ‖ sophisticated auditory–motor learning released [3h]acetic acid institut albert bonniot cyclic tetrapeptide antibiotics α-aminosuberic acid chap half-maximal inhibitory concentrations citation information faculté de médecine 10-epoxy-8-oxodecanoic acid asu structure-activity relationship study potent enzyme-inhibiting group active-site residues download pdf b16/bl6 cells share cyclic tetrapeptide portion ile-d-pro]} pnas web site cyclic tetrapeptide antibiotic
Social Networks {👍}(4)
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