DOI . ORG {
}
We began analyzing https://pnas.org/doi/full/10.1073/pnas.201208798, but it redirected us to https://pnas.org/doi/full/10.1073/pnas.201208798. The analysis below is for the second page.
Title[redir]:
Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals | PNAS
Description:
BH3-only proteins function at a proximal point in a conserved cell death pathway by binding, through their BH3 domains, to other Bcl-2 family members and triggering mitochondrial events associated ...
Title[redir]:
Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals | PNAS
Description:
BH3-only proteins function at a proximal point in a conserved cell death pathway by binding, through their BH3 domains, to other Bcl-2 family members and triggering mitochondrial events associated ...
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Keywords {🔍}
bbc, cell, cells, expression, serum, death, pubmed, google, scholar, crossref, fig, bhonly, promoter, protein, mrna, levels, growth, binding, cdna, research, proteins, proapoptotic, control, human, gene, bcl, apoptosis, dna, activity, analysis, factor, egl, shown, induced, blot, site, wildtype, region, presence, igf, bclxl, luciferase, function, antiapoptotic, domain, reporter, view, stimuli, tumor, activation,
Topics {✒️}
flag-epitope-tagged bcl-xl flag epitope-tagged bcl-xl egg-laying-defective-1 note temperature-sensitive p53-val135 mutant β-galactosidase reporter pcmvβ-gal providing hela/bcl-xl cells potent anti-apoptotic properties plasmid-encoding wild-type p53 jan-willem van ittersum ft-bcl-xl expression plasmids flag-epitope tagged bbc3 transfected hela/bcl-xl cells recombinant glutathione s-transferase platelet-derived growth factor broad-spectrum caspase inhibitor sustained anti-apoptotic signal serine/threonine kinase akt assumes wild-type conformation p53-estrogen receptor fusion references 1 anti-apoptotic growth factors includes bcl-2-interacting killer abbreviations bh3 pcdna3/ha-bbc3-ala plasmid pro-apoptotic bcl-2 homolog pi 3-kinase-dependent pathways temperature-sensitive mutant p53 β-galactosidase marker plasmid broad anti-apoptotic activity ha epitope-tagged form anti-bcl-xl antibodies caspase inhibitor z-vad β-gal-marked cells strong pro-apoptotic stimulus p53-independent apoptotic stimuli 20 abstract materials strongly pro-apoptotic bh3 hela/bcl-xl cells hela-bcl-xl cells methods isolation luciferase/β-galactosidase levels wild-type p53 activity full-length bbc3 orf recombinant gst-bcl-xl 9-kb ecori/bamhi fragment 17-kb psti/bamhi fragment mammalian pro-apoptotic bh3 social media facebook wild-type p53 function bcl-2-interacting killer bad
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