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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
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We began analyzing https://www.nature.com/articles/5200797, but it redirected us to https://www.nature.com/articles/5200797. The analysis below is for the second page.

Title[redir]:
Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa | European Journal of Human Genetics
Description:
The RP9 form of autosomal dominant retinitis pigmentosa (adRP) maps to a locus on human chromosome 7p14. We now report two different disease associated mutations in a previously unidentified human gene, the mouse orthologue of which has been characterised by its interaction with the Pim-1 oncogene. In the original linked family we identified the missense mutation H137L. A second missense mutation, D170G, was found in a single RP patient. The putative RP9 gene appears to be expressed in a wide range of tissues, but its function is unknown and a pathogenic mechanism remains to be determined.

Matching Content Categories {📚}

  • Science
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Content Management System {📝}

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Custom-built

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🌠 Phenomenal Traffic: 5M - 10M visitors per month


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Keywords {🔍}

gene, article, retinitis, pigmentosa, protein, human, mouse, google, scholar, nature, dominant, cas, mutations, sequence, pim, autosomal, disease, residues, figure, retinal, shown, genet, analysis, data, keen, chromosome, identified, sequences, present, polymorphism, content, form, locus, family, mutation, genomic, patients, region, dna, genes, cir, conserved, exon, control, splicing, cookies, function, change, inglehearn, previously,

Topics {✒️}

nature portfolio permissions reprints privacy policy crispr/cas9-based mouse model retinal cdna libraries visual system development advertising open reading frame nature social media author information authors pre-mrna splicing factors author correspondence x-linked recessive modes emboss software suite permissions single-strand conformation polymorphism regional form putative mrna sequence �regional’ loss regional duplication mouse model bearing privacy retinitis pigmentosa european economic area transcriptional control complex journals search log specific physiological context explore content similar content full size image inverclyde royal hospital photoactivated molecular species inherited retinal degenerations multiple loci accounting erythrocyte pyrimidine 5-nucleotidase k210r polymorphism highlighted originally provoked interest high metabolic rate yac contig spanning cag repeat expansion bardet–biedl syndrome 9 accepting optional cookies developing avian retina disrupted alternative splicing inherited retinal dystrophies single rp patient expression profile based cgmp-binding domain washington genome center

Questions {❓}

  • Nuclear targeting sequences–a consensus?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa
         description:The RP9 form of autosomal dominant retinitis pigmentosa (adRP) maps to a locus on human chromosome 7p14. We now report two different disease associated mutations in a previously unidentified human gene, the mouse orthologue of which has been characterised by its interaction with the Pim-1 oncogene. In the original linked family we identified the missense mutation H137L. A second missense mutation, D170G, was found in a single RP patient. The putative RP9 gene appears to be expressed in a wide range of tissues, but its function is unknown and a pathogenic mechanism remains to be determined.
         datePublished:2002-05-24T00:00:00Z
         dateModified:2002-05-24T00:00:00Z
         pageStart:245
         pageEnd:249
         sameAs:https://doi.org/10.1038/sj.ejhg.5200797
         keywords:
            RP9
            retinitis
            pigmentosa
            Pim-1
            Biomedicine
            general
            Human Genetics
            Bioinformatics
            Gene Expression
            Cytogenetics
         image:
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            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.ejhg.5200797/MediaObjects/41431_2002_Article_BF5200797_Fig2_HTML.jpg
         isPartOf:
            name:European Journal of Human Genetics
            issn:
               1476-5438
               1018-4813
            volumeNumber:10
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer International Publishing
            logo:
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               type:ImageObject
            type:Organization
         author:
               name:T Jeffrey Keen
               affiliation:
                     name:Molecular Medicine Unit, University of Leeds
                     address:
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                        type:PostalAddress
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                        name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
                        type:PostalAddress
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                        name:Department of Ophthalmology, Leeds General Infirmary, Leeds, UK
                        type:PostalAddress
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                     name:CERA, Victorian Eye and Ear Hospital
                     address:
                        name:CERA, Victorian Eye and Ear Hospital, Melbourne, Australia
                        type:PostalAddress
                     type:Organization
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               name:David C Mansfield
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                     name:Inverclyde Royal Hospital
                     address:
                        name:Department of Ophthalmology, Inverclyde Royal Hospital, Greenock, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Robert F Mueller
               affiliation:
                     name:Molecular Medicine Unit, University of Leeds
                     address:
                        name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                        type:PostalAddress
                     type:Organization
                     name:St. James's University Hospital
                     address:
                        name:Department of Clinical Genetics, St. James's University Hospital, Leeds, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Shomi S Bhattacharya
               affiliation:
                     name:Institute of Ophthalmology
                     address:
                        name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Alan C Bird
               affiliation:
                     name:Institute of Ophthalmology
                     address:
                        name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Alexander F Markham
               affiliation:
                     name:Molecular Medicine Unit, University of Leeds
                     address:
                        name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Chris F Inglehearn
               affiliation:
                     name:Molecular Medicine Unit, University of Leeds
                     address:
                        name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa
      description:The RP9 form of autosomal dominant retinitis pigmentosa (adRP) maps to a locus on human chromosome 7p14. We now report two different disease associated mutations in a previously unidentified human gene, the mouse orthologue of which has been characterised by its interaction with the Pim-1 oncogene. In the original linked family we identified the missense mutation H137L. A second missense mutation, D170G, was found in a single RP patient. The putative RP9 gene appears to be expressed in a wide range of tissues, but its function is unknown and a pathogenic mechanism remains to be determined.
      datePublished:2002-05-24T00:00:00Z
      dateModified:2002-05-24T00:00:00Z
      pageStart:245
      pageEnd:249
      sameAs:https://doi.org/10.1038/sj.ejhg.5200797
      keywords:
         RP9
         retinitis
         pigmentosa
         Pim-1
         Biomedicine
         general
         Human Genetics
         Bioinformatics
         Gene Expression
         Cytogenetics
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.ejhg.5200797/MediaObjects/41431_2002_Article_BF5200797_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsj.ejhg.5200797/MediaObjects/41431_2002_Article_BF5200797_Fig2_HTML.jpg
      isPartOf:
         name:European Journal of Human Genetics
         issn:
            1476-5438
            1018-4813
         volumeNumber:10
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer International Publishing
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:T Jeffrey Keen
            affiliation:
                  name:Molecular Medicine Unit, University of Leeds
                  address:
                     name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Matthew M Hims
            affiliation:
                  name:Molecular Medicine Unit, University of Leeds
                  address:
                     name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Arthur B McKie
            affiliation:
                  name:Molecular Medicine Unit, University of Leeds
                  address:
                     name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Anthony T Moore
            affiliation:
                  name:Institute of Ophthalmology
                  address:
                     name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Rob M Doran
            affiliation:
                  name:Leeds General Infirmary
                  address:
                     name:Department of Ophthalmology, Leeds General Infirmary, Leeds, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:David A Mackey
            affiliation:
                  name:CERA, Victorian Eye and Ear Hospital
                  address:
                     name:CERA, Victorian Eye and Ear Hospital, Melbourne, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:David C Mansfield
            affiliation:
                  name:Inverclyde Royal Hospital
                  address:
                     name:Department of Ophthalmology, Inverclyde Royal Hospital, Greenock, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Robert F Mueller
            affiliation:
                  name:Molecular Medicine Unit, University of Leeds
                  address:
                     name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                     type:PostalAddress
                  type:Organization
                  name:St. James's University Hospital
                  address:
                     name:Department of Clinical Genetics, St. James's University Hospital, Leeds, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Shomi S Bhattacharya
            affiliation:
                  name:Institute of Ophthalmology
                  address:
                     name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Alan C Bird
            affiliation:
                  name:Institute of Ophthalmology
                  address:
                     name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Alexander F Markham
            affiliation:
                  name:Molecular Medicine Unit, University of Leeds
                  address:
                     name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Chris F Inglehearn
            affiliation:
                  name:Molecular Medicine Unit, University of Leeds
                  address:
                     name:Molecular Medicine Unit, University of Leeds, Leeds, UK
                     type:PostalAddress
                  type:Organization
            type:Person
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      name:European Journal of Human Genetics
      issn:
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      volumeNumber:10
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      name:Springer International Publishing
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      name:Molecular Medicine Unit, University of Leeds
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         name:Molecular Medicine Unit, University of Leeds, Leeds, UK
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      address:
         name:Molecular Medicine Unit, University of Leeds, Leeds, UK
         type:PostalAddress
      name:Institute of Ophthalmology
      address:
         name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
         type:PostalAddress
      name:Leeds General Infirmary
      address:
         name:Department of Ophthalmology, Leeds General Infirmary, Leeds, UK
         type:PostalAddress
      name:CERA, Victorian Eye and Ear Hospital
      address:
         name:CERA, Victorian Eye and Ear Hospital, Melbourne, Australia
         type:PostalAddress
      name:Inverclyde Royal Hospital
      address:
         name:Department of Ophthalmology, Inverclyde Royal Hospital, Greenock, UK
         type:PostalAddress
      name:Molecular Medicine Unit, University of Leeds
      address:
         name:Molecular Medicine Unit, University of Leeds, Leeds, UK
         type:PostalAddress
      name:St. James's University Hospital
      address:
         name:Department of Clinical Genetics, St. James's University Hospital, Leeds, UK
         type:PostalAddress
      name:Institute of Ophthalmology
      address:
         name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
         type:PostalAddress
      name:Institute of Ophthalmology
      address:
         name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
         type:PostalAddress
      name:Molecular Medicine Unit, University of Leeds
      address:
         name:Molecular Medicine Unit, University of Leeds, Leeds, UK
         type:PostalAddress
      name:Molecular Medicine Unit, University of Leeds
      address:
         name:Molecular Medicine Unit, University of Leeds, Leeds, UK
         type:PostalAddress
ImageObject:
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Person:
      name:T Jeffrey Keen
      affiliation:
            name:Molecular Medicine Unit, University of Leeds
            address:
               name:Molecular Medicine Unit, University of Leeds, Leeds, UK
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Matthew M Hims
      affiliation:
            name:Molecular Medicine Unit, University of Leeds
            address:
               name:Molecular Medicine Unit, University of Leeds, Leeds, UK
               type:PostalAddress
            type:Organization
      name:Arthur B McKie
      affiliation:
            name:Molecular Medicine Unit, University of Leeds
            address:
               name:Molecular Medicine Unit, University of Leeds, Leeds, UK
               type:PostalAddress
            type:Organization
      name:Anthony T Moore
      affiliation:
            name:Institute of Ophthalmology
            address:
               name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
               type:PostalAddress
            type:Organization
      name:Rob M Doran
      affiliation:
            name:Leeds General Infirmary
            address:
               name:Department of Ophthalmology, Leeds General Infirmary, Leeds, UK
               type:PostalAddress
            type:Organization
      name:David A Mackey
      affiliation:
            name:CERA, Victorian Eye and Ear Hospital
            address:
               name:CERA, Victorian Eye and Ear Hospital, Melbourne, Australia
               type:PostalAddress
            type:Organization
      name:David C Mansfield
      affiliation:
            name:Inverclyde Royal Hospital
            address:
               name:Department of Ophthalmology, Inverclyde Royal Hospital, Greenock, UK
               type:PostalAddress
            type:Organization
      name:Robert F Mueller
      affiliation:
            name:Molecular Medicine Unit, University of Leeds
            address:
               name:Molecular Medicine Unit, University of Leeds, Leeds, UK
               type:PostalAddress
            type:Organization
            name:St. James's University Hospital
            address:
               name:Department of Clinical Genetics, St. James's University Hospital, Leeds, UK
               type:PostalAddress
            type:Organization
      name:Shomi S Bhattacharya
      affiliation:
            name:Institute of Ophthalmology
            address:
               name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
               type:PostalAddress
            type:Organization
      name:Alan C Bird
      affiliation:
            name:Institute of Ophthalmology
            address:
               name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
               type:PostalAddress
            type:Organization
      name:Alexander F Markham
      affiliation:
            name:Molecular Medicine Unit, University of Leeds
            address:
               name:Molecular Medicine Unit, University of Leeds, Leeds, UK
               type:PostalAddress
            type:Organization
      name:Chris F Inglehearn
      affiliation:
            name:Molecular Medicine Unit, University of Leeds
            address:
               name:Molecular Medicine Unit, University of Leeds, Leeds, UK
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Molecular Medicine Unit, University of Leeds, Leeds, UK
      name:Molecular Medicine Unit, University of Leeds, Leeds, UK
      name:Molecular Medicine Unit, University of Leeds, Leeds, UK
      name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
      name:Department of Ophthalmology, Leeds General Infirmary, Leeds, UK
      name:CERA, Victorian Eye and Ear Hospital, Melbourne, Australia
      name:Department of Ophthalmology, Inverclyde Royal Hospital, Greenock, UK
      name:Molecular Medicine Unit, University of Leeds, Leeds, UK
      name:Department of Clinical Genetics, St. James's University Hospital, Leeds, UK
      name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
      name:Department of Molecular Genetics, Institute of Ophthalmology, London, UK
      name:Molecular Medicine Unit, University of Leeds, Leeds, UK
      name:Molecular Medicine Unit, University of Leeds, Leeds, UK

Social Networks {👍}(1)

External Links {🔗}(200)

Analytics and Tracking {📊}

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Libraries {📚}

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Mail Servers:

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Name Servers:

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CDN Services {📦}

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3.78s.