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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. Social Networks
  10. External Links
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We began analyzing https://www.nature.com/articles/onc2009511, but it redirected us to https://www.nature.com/articles/onc2009511. The analysis below is for the second page.

Title[redir]:
Lysine methylation regulates the pRb tumour suppressor protein | Oncogene
Description:
The pRb tumour suppressor protein has a central role in coordinating early cell cycle progression. An important level of control imposed on pRb occurs through post-translational modification, for example, phosphorylation. We describe here a new level of regulation on pRb, mediated through the targeted methylation of lysine residues, by the methyltransferase Set7/9. Set7/9 methylates the C-terminal region of pRb, both in vitro and in cells, and methylated pRb interacts with heterochromatin protein HP1. pRb methylation is required for pRb-dependent cell cycle arrest and transcriptional repression, as well as pRb-dependent differentiation. Our results indicate that methylation can influence the properties of pRb, and raise the interesting possibility that methylation modulates pRb tumour suppressor activity.

Matching Content Categories {📚}

  • Education
  • Telecommunications
  • Health & Fitness

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Doi.org Make Money? {💸}

We can't figure out the monetization strategy.

Some websites aren't about earning revenue; they're built to connect communities or raise awareness. There are numerous motivations behind creating websites. This might be one of them. Doi.org might have a hidden revenue stream, but it's not something we can detect.

Keywords {🔍}

pubmed, article, google, scholar, cas, cell, nature, protein, methylation, retinoblastoma, prb, central, differentiation, cancer, access, thangue, mol, oncogene, lysine, biol, histone, content, tumour, suppressor, set, cookies, information, cycle, regulation, gene, privacy, control, required, transcription, supplementary, function, data, regulates, munro, progression, methyltransferase, cells, arrest, activity, open, acetylation, wang, van, development, lee,

Topics {✒️}

nature portfolio permissions reprints privacy policy retinoblastoma tumour-suppressor protein advertising social media author information authors retinoblastoma tumour suppressor nature 352 nature 432 nature 359 nature 425 nature 412 nature 419 nature 358 nature author correspondence mef2-dependent gene expression dna-damage-responsive acetylation personal data springerlink instant access supplementary figures 1i lysine methylation regulates data protection heterochromatin protein hp1 set7 lysine methyltransferase permissions position-dependent transcriptional regulation e2f transactivation domain murine development methylated prb interacts rb lxcxe-binding function retinoblastoma protein acts van der valk cell-cycle arrest retinoblastoma gene product prb controls proliferation supplementary figure legend retinoblastoma protein switches retinoblastoma gene family cell cycle progression privacy human tumor xenografts histone methyltransferase set7/9 cell cycle control central role c-terminal region issue learn c-terminal truncation set9-mediated methylation

Schema {🗺️}

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         description:The pRb tumour suppressor protein has a central role in coordinating early cell cycle progression. An important level of control imposed on pRb occurs through post-translational modification, for example, phosphorylation. We describe here a new level of regulation on pRb, mediated through the targeted methylation of lysine residues, by the methyltransferase Set7/9. Set7/9 methylates the C-terminal region of pRb, both in vitro and in cells, and methylated pRb interacts with heterochromatin protein HP1. pRb methylation is required for pRb-dependent cell cycle arrest and transcriptional repression, as well as pRb-dependent differentiation. Our results indicate that methylation can influence the properties of pRb, and raise the interesting possibility that methylation modulates pRb tumour suppressor activity.
         datePublished:2010-02-08T00:00:00Z
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      headline:Lysine methylation regulates the pRb tumour suppressor protein
      description:The pRb tumour suppressor protein has a central role in coordinating early cell cycle progression. An important level of control imposed on pRb occurs through post-translational modification, for example, phosphorylation. We describe here a new level of regulation on pRb, mediated through the targeted methylation of lysine residues, by the methyltransferase Set7/9. Set7/9 methylates the C-terminal region of pRb, both in vitro and in cells, and methylated pRb interacts with heterochromatin protein HP1. pRb methylation is required for pRb-dependent cell cycle arrest and transcriptional repression, as well as pRb-dependent differentiation. Our results indicate that methylation can influence the properties of pRb, and raise the interesting possibility that methylation modulates pRb tumour suppressor activity.
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Social Networks {👍}(1)

External Links {🔗}(267)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

4.6s.