DOI . ORG {}

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We began analyzing https://www.nature.com/articles/ni0801_725, but it redirected us to https://www.nature.com/articles/ni0801_725. The analysis below is for the second page.

Title[redir]:
Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen | Nature Immunology
Description:
Respiratory exposure to allergen induces T cell tolerance and protection against the development of airway hyperreactivity and asthma. However, the specific mechanisms by which tolerance is induced by respiratory allergen are not clear. We report here that pulmonary dendritic cells (DCs) from mice exposed to respiratory antigen transiently produced interleukin 10 (IL-10). These phenotypically mature pulmonary DCs, which were B-7hi as well as producing IL-10, stimulated the development of CD4+ T regulatory 1–like cells that also produced high amounts of IL-10. In addition, adoptive transfer of pulmonary DCs from IL-10+/+, but not IL-10−/−, mice exposed to respiratory antigen induced antigen-specific unresponsiveness in recipient mice. These studies show that IL-10 production by DCs is critical for the induction of tolerance, and that phenotypically mature pulmonary DCs mediate tolerance induced by respiratory exposure to antigen.

Matching Content Categories {📚}

Science
Education
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Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Doi.org Make Money? {💸}

We see no obvious way the site makes money.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Doi.org could be secretly minting cash, but we can't detect the process.

Keywords {🔍}

article, cas, google, scholar, cells, dendritic, nature, immunol, cell, antigen, tolerance, med, exp, access, respiratory, content, immunology, pulmonary, umetsu, mice, induction, cookies, induced, dekruyff, airway, interleukin, lung, vivo, pubmed, privacy, exposure, asthma, dcs, regulatory, responses, allergy, mouse, cytokine, tcell, vitro, function, data, mechanisms, open, holt, inhaled, clin, immunity, differentiation, mucosal,

Topics {✒️}

nature portfolio permissions reprints privacy policy granulocyte-macrophage colony-stimulating factor granulocyte/macrophage colony-stimulating factor advertising social media nature med antigen-induced airway hyperresponsiveness author information authors nature 376 nature 389 nature 397 nature 402 nature class i-restricted cd8+ monoclonal anti-idiotype antibodies author correspondence monocyte-derived cd1a+ eosinophilic airway inflammation springerlink instant access personal data inducible t-cell cell clones induced pulmonary dendritic cells permissions data protection respiratory tract william dendritic cell subsets mouse bone marrow development lymphokine-producing potential thymic dendritic cells dendritic cell progeny dendritic cell subtypes endogenous macrophage populations human dendritic cells recombinant adenovirus suppressed privacy california lung association human airway epithelium t-cell antigen-presenting activities orally administered antigen b-7hi produced high amounts tcr transgenic model cell stimulatory capacity cell lymphoma 38c13 mouse lymphoid organs

Schema {🗺️}

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External Links {🔗}(204)

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