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  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s40820-024-01477-3, but it redirected us to https://link.springer.com/article/10.1007/s40820-024-01477-3. The analysis below is for the second page.

Title[redir]:
Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases | Nano-Micro Letters
Description:
The eye, a complex organ isolated from the systemic circulation, presents significant drug delivery challenges owing to its protective mechanisms, such as the blood-retinal barrier and corneal impermeability. Conventional drug administration methods often fail to sustain therapeutic levels and may compromise patient safety and compliance. Polysaccharide-based microneedles (PSMNs) have emerged as a transformative solution for ophthalmic drug delivery. However, a comprehensive review of PSMNs in ophthalmology has not been published to date. In this review, we critically examine the synergy between polysaccharide chemistry and microneedle technology for enhancing ocular drug delivery. We provide a thorough analysis of PSMNs, summarizing the design principles, fabrication processes, and challenges addressed during fabrication, including improving patient comfort and compliance. We also describe recent advances and the performance of various PSMNs in both research and clinical scenarios. Finally, we review the current regulatory frameworks and market barriers that are relevant to the clinical and commercial advancement of PSMNs and provide a final perspective on this research area.

Matching Content Categories {šŸ“š}

  • Education
  • Science
  • Virtual Reality

Content Management System {šŸ“}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {šŸ“ˆ}

What is the average monthly size of doi.org audience?

šŸŒ  Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Doi.org Make Money? {šŸ’ø}

We're unsure how the site profits.

Not every website is profit-driven; some are created to spread information or serve as an online presence. Websites can be made for many reasons. This could be one of them. Doi.org might be earning cash quietly, but we haven't detected the monetization method.

Keywords {šŸ”}

drug, article, scholar, google, delivery, mns, microneedles, ocular, microneedle, release, psmns, applications, eye, fig, polysaccharides, transdermal, treatment, copyright, reproduced, fabrication, therapeutic, properties, potential, polysaccharide, sci, acid, printing, polymer, mater, systems, mechanical, zhang, wang, technology, lee, materials, hyaluronic, application, adv, dissolving, skin, design, permission, process, control, efficacy, size, int, diseases, review,

Topics {āœ’ļø}

implantable double-layered micro-drug-reservoirs semi-interpenetrating network-based microneedle ultra-small platinum-ruthenium nanoalloys hollow microneedle-mediated micro-injections serpentine-shaped semi-solid microneedle chemically cross-linking alg-apba targeting virus-inspired nanodrug cell-penetrating tumor-targeting peptide age-related macular degeneration successfully delivered micro-sized formed glucose-responsive complexes claw-inspired microneedle patches cerium/zinc-based composites polymer-peptide conjugate system chitosan/arginineā€“chitosan polymer blends microneedle-mediated protein delivery mxene-doped conductive hydrogel globefish-inspired balloon catheter contact lens-shaped microneedles explore polymer-coated mns dual-drug loading system hyaluronic acid-based microneedle fast-dissolving microneedle systems polysaccharide-based microneedle systems hyaluronic acid-silica composites drug-eluting balloons maximizes direct-ink-writing 3d printing anti-pd-1ā€“cisplatin nanoparticles mn-mediated drug delivery sars-cov-2 spike protein enable real-time monitoring combating antibiotic-resistant pathogens including drug-loaded nanoparticles water-soluble danshen extracts cs-based contact lens pressure-mediated drug delivery d-glucuronic acid linked anti-angiogenic monoclonal antibody tear-soluble contact lens porous special-shaped microneedles hyaluronic acid-based microneedles microneedle-based drug delivery bilaterally augmented sono-chemodynamic lĆ³pez-de la rosa microneedle-based natural polysaccharide tip-loaded dissolving microneedles mucosa-adhesive polysaccharide nanoparticles dual-release psmn patch time-dependent administration efficiencies chitosan-based microneedle arrays

Questions {ā“}

  • Can Microneedles Revolutionize Ocular Drug Delivery?

Schema {šŸ—ŗļø}

WebPage:
      mainEntity:
         headline:Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases
         description: The eye, a complex organ isolated from the systemic circulation, presents significant drug delivery challenges owing to its protective mechanisms, such as the blood-retinal barrier and corneal impermeability. Conventional drug administration methods often fail to sustain therapeutic levels and may compromise patient safety and compliance. Polysaccharide-based microneedles (PSMNs) have emerged as a transformative solution for ophthalmic drug delivery. However, a comprehensive review of PSMNs in ophthalmology has not been published to date. In this review, we critically examine the synergy between polysaccharide chemistry and microneedle technology for enhancing ocular drug delivery. We provide a thorough analysis of PSMNs, summarizing the design principles, fabrication processes, and challenges addressed during fabrication, including improving patient comfort and compliance. We also describe recent advances and the performance of various PSMNs in both research and clinical scenarios. Finally, we review the current regulatory frameworks and market barriers that are relevant to the clinical and commercial advancement of PSMNs and provide a final perspective on this research area.
         datePublished:2024-08-13T00:00:00Z
         dateModified:2024-08-13T00:00:00Z
         pageStart:1
         pageEnd:52
         license:http://creativecommons.org/licenses/by/4.0/
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            Ocular delivery
            Polysaccharide
            Microneedles
            Drug administration
            Nanotechnology and Microengineering
            Nanotechnology
            Nanoscale Science and Technology
            Energy
            general
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         isPartOf:
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            issn:
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               type:ImageObject
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         author:
               name:Qingdong Bao
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                     name:Eye Institute of Shandong First Medical University
                     address:
                        name:State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
                     name:Eye Hospital of Shandong First Medical University
                     address:
                        name:Eye Hospital of Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
                     name:Shandong First Medical University
                     address:
                        name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Xiaoting Zhang
               affiliation:
                     name:Chinese Academy of Sciences
                     address:
                        name:State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
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               name:Zhankun Hao
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                     address:
                        name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                        type:PostalAddress
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               name:Qinghua Li
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                     name:Eye Institute of Shandong First Medical University
                     address:
                        name:State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, Peopleā€™s Republic of China
                        type:PostalAddress
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                     name:Eye Hospital of Shandong First Medical University
                     address:
                        name:Eye Hospital of Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
                     name:Shandong First Medical University
                     address:
                        name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                        type:PostalAddress
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               name:Fan Wu
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                     address:
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                        type:PostalAddress
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               type:Person
               name:Kaiyuan Wang
               affiliation:
                     name:National University of Singapore
                     address:
                        name:Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Yang Li
               affiliation:
                     name:Chinese Academy of Sciences
                     address:
                        name:State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Wenlong Li
               affiliation:
                     name:Eye Institute of Shandong First Medical University
                     address:
                        name:State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
                     name:Eye Hospital of Shandong First Medical University
                     address:
                        name:Eye Hospital of Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
                     name:Shandong First Medical University
                     address:
                        name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
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               type:Person
               name:Hua Gao
               affiliation:
                     name:Eye Institute of Shandong First Medical University
                     address:
                        name:State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
                     name:Eye Hospital of Shandong First Medical University
                     address:
                        name:Eye Hospital of Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                        type:PostalAddress
                     type:Organization
                     name:Shandong First Medical University
                     address:
                        name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
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ScholarlyArticle:
      headline:Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases
      description: The eye, a complex organ isolated from the systemic circulation, presents significant drug delivery challenges owing to its protective mechanisms, such as the blood-retinal barrier and corneal impermeability. Conventional drug administration methods often fail to sustain therapeutic levels and may compromise patient safety and compliance. Polysaccharide-based microneedles (PSMNs) have emerged as a transformative solution for ophthalmic drug delivery. However, a comprehensive review of PSMNs in ophthalmology has not been published to date. In this review, we critically examine the synergy between polysaccharide chemistry and microneedle technology for enhancing ocular drug delivery. We provide a thorough analysis of PSMNs, summarizing the design principles, fabrication processes, and challenges addressed during fabrication, including improving patient comfort and compliance. We also describe recent advances and the performance of various PSMNs in both research and clinical scenarios. Finally, we review the current regulatory frameworks and market barriers that are relevant to the clinical and commercial advancement of PSMNs and provide a final perspective on this research area.
      datePublished:2024-08-13T00:00:00Z
      dateModified:2024-08-13T00:00:00Z
      pageStart:1
      pageEnd:52
      license:http://creativecommons.org/licenses/by/4.0/
      sameAs:https://doi.org/10.1007/s40820-024-01477-3
      keywords:
         Ocular delivery
         Polysaccharide
         Microneedles
         Drug administration
         Nanotechnology and Microengineering
         Nanotechnology
         Nanoscale Science and Technology
         Energy
         general
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      isPartOf:
         name:Nano-Micro Letters
         issn:
            2150-5551
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            Periodical
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            name:Qingdong Bao
            affiliation:
                  name:Eye Institute of Shandong First Medical University
                  address:
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                     type:PostalAddress
                  type:Organization
                  name:Eye Hospital of Shandong First Medical University
                  address:
                     name:Eye Hospital of Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
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                     type:PostalAddress
                  type:Organization
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            name:Zhankun Hao
            affiliation:
                  name:Shandong First Medical University
                  address:
                     name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Qinghua Li
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                  name:Eye Institute of Shandong First Medical University
                  address:
                     name:State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
                  name:Eye Hospital of Shandong First Medical University
                  address:
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                     type:PostalAddress
                  type:Organization
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                  address:
                     name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
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            type:Person
            name:Fan Wu
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                  address:
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                     type:PostalAddress
                  type:Organization
            type:Person
            name:Yang Li
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                  name:Chinese Academy of Sciences
                  address:
                     name:State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Wenlong Li
            affiliation:
                  name:Eye Institute of Shandong First Medical University
                  address:
                     name:State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
                  name:Eye Hospital of Shandong First Medical University
                  address:
                     name:Eye Hospital of Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
                  name:Shandong First Medical University
                  address:
                     name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Hua Gao
            affiliation:
                  name:Eye Institute of Shandong First Medical University
                  address:
                     name:State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
                  name:Eye Hospital of Shandong First Medical University
                  address:
                     name:Eye Hospital of Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                     type:PostalAddress
                  type:Organization
                  name:Shandong First Medical University
                  address:
                     name:College of Ophthalmology, Shandong First Medical University, Jinan, Peopleā€™s Republic of China
                     type:PostalAddress
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