Here's how DOI.ORG makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s11883-021-00907-6, but it redirected us to https://link.springer.com/article/10.1007/s11883-021-00907-6. The analysis below is for the second page.

Title[redir]:
The Role of Phospholipid Transfer Protein in the Development of Atherosclerosis | Current Atherosclerosis Reports
Description:
Purpose of Review Phospholipid transfer protein (PLTP), a member of lipid transfer protein family, is an important protein involved in lipid metabolism in the circulation. This article reviews recent PLTP research progresses, involving lipoprotein metabolism and atherogenesis. Recent Findings PLTP activity influences atherogenic and anti-atherogenic lipoprotein levels. Human serum PLTP activity is a risk factor for human cardiovascular disease and is an independent predictor of all-cause mortality. PLTP deficiency reduces VLDL and LDL levels and attenuates atherosclerosis in mouse models, while PLTP overexpression exerts an opposite effect. Both PLTP deficiency and overexpression result in reduction of HDL which has different size, inflammatory index, and lipid composition. Moreover, although both PLTP deficiency and overexpression reduce cholesterol efflux capacity, but this effect has no impact in macrophage reverse cholesterol transport in mice. Furthermore, PLTP activity is related with metabolic syndrome, thrombosis, and inflammation. Summary PLTP could be target for the treatment of dyslipidemia and atherosclerosis, although some potential off-target effects should be noted.

Matching Content Categories {📚}

  • Health & Fitness
  • Education
  • Careers

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 80,904,851 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Doi.org Make Money? {💸}

We see no obvious way the site makes money.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Doi.org could have a money-making trick up its sleeve, but it's undetectable for now.

Keywords {🔍}

pubmed, article, google, scholar, cas, transfer, protein, phospholipid, plasma, biol, pltp, lipid, van, atherosclerosis, central, lipoprotein, human, res, jiang, deficiency, mice, chem, activity, hdl, high, thromb, density, arterioscler, vasc, metabolism, levels, lipoproteins, disease, cholesterol, risk, albers, cell, tol, cardiovascular, patients, cells, chen, wang, content, role, biophys, desrumaux, jauhiainen, deckert, gent,

Topics {✒️}

ox-ldl-induced tgf-beta1 production high-density lipoprotein production month download article/chapter low-density lipoprotein production endothelium-protective sphingosine-1-phosphate provided phospholipid-transfer protein deficiency high-density lipoprotein size xian-cheng jiang bactericidal/permeability-increasing protein lipid/lipoprotein plasma levels abca1-dependent cholesterol efflux high density lipoprotein pltp-null background promotes anti-atherogenic lipoprotein levels low density lipoprotein ras/erk/pltp pathway pltp-mediated hdl conversion cardiovascular disease susceptibility carotid intima-media thickness phospholipid transfer protein high density lipoproteins human monocyte-derived macrophages high cholesterol diet metabolic syndrome low density lipoproteins adenovirus-mediated overexpression diet-induced atherosclerosis phospholipid transfer activity full article pdf promote platelet aggregation unexpected metabolic complications involving lipoprotein metabolism elevated plasma levels coronary heart diseases vascular biology access blood-brain barrier net mass transfer biochim biophys acta receptor target expressed high pltp activity privacy choices/manage cookies plasma cholesteryl esters enhances cholesterol efflux lofton-day ce lipid transfer proteins article jiang plasma lipoproteins responsible cholesterol efflux capacity pltp deficiency improves nondiabetic control subjects

Questions {❓}

  • Phospholipid transfer protein, an emerging cardiometabolic risk marker: is it time to intervene?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:The Role of Phospholipid Transfer Protein in the Development of Atherosclerosis
         description:Phospholipid transfer protein (PLTP), a member of lipid transfer protein family, is an important protein involved in lipid metabolism in the circulation. This article reviews recent PLTP research progresses, involving lipoprotein metabolism and atherogenesis. PLTP activity influences atherogenic and anti-atherogenic lipoprotein levels. Human serum PLTP activity is a risk factor for human cardiovascular disease and is an independent predictor of all-cause mortality. PLTP deficiency reduces VLDL and LDL levels and attenuates atherosclerosis in mouse models, while PLTP overexpression exerts an opposite effect. Both PLTP deficiency and overexpression result in reduction of HDL which has different size, inflammatory index, and lipid composition. Moreover, although both PLTP deficiency and overexpression reduce cholesterol efflux capacity, but this effect has no impact in macrophage reverse cholesterol transport in mice. Furthermore, PLTP activity is related with metabolic syndrome, thrombosis, and inflammation. PLTP could be target for the treatment of dyslipidemia and atherosclerosis, although some potential off-target effects should be noted.
         datePublished:2021-01-26T00:00:00Z
         dateModified:2021-01-26T00:00:00Z
         pageStart:1
         pageEnd:9
         sameAs:https://doi.org/10.1007/s11883-021-00907-6
         keywords:
            Phospholipid transfer protein
            Very low-density lipoprotein production
            High-density lipoprotein metabolism
            Atherosclerosis
            Metabolic syndrome
            Angiology
            Cardiology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11883-021-00907-6/MediaObjects/11883_2021_907_Fig1_HTML.png
         isPartOf:
            name:Current Atherosclerosis Reports
            issn:
               1534-6242
               1523-3804
            volumeNumber:23
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Xian-Cheng Jiang
               affiliation:
                     name:SUNY Downstate Health Sciences University
                     address:
                        name:Department of Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Yang Yu
               affiliation:
                     name:Shandong First Medical University & Shandong Academy of Medical Sciences
                     address:
                        name:Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:The Role of Phospholipid Transfer Protein in the Development of Atherosclerosis
      description:Phospholipid transfer protein (PLTP), a member of lipid transfer protein family, is an important protein involved in lipid metabolism in the circulation. This article reviews recent PLTP research progresses, involving lipoprotein metabolism and atherogenesis. PLTP activity influences atherogenic and anti-atherogenic lipoprotein levels. Human serum PLTP activity is a risk factor for human cardiovascular disease and is an independent predictor of all-cause mortality. PLTP deficiency reduces VLDL and LDL levels and attenuates atherosclerosis in mouse models, while PLTP overexpression exerts an opposite effect. Both PLTP deficiency and overexpression result in reduction of HDL which has different size, inflammatory index, and lipid composition. Moreover, although both PLTP deficiency and overexpression reduce cholesterol efflux capacity, but this effect has no impact in macrophage reverse cholesterol transport in mice. Furthermore, PLTP activity is related with metabolic syndrome, thrombosis, and inflammation. PLTP could be target for the treatment of dyslipidemia and atherosclerosis, although some potential off-target effects should be noted.
      datePublished:2021-01-26T00:00:00Z
      dateModified:2021-01-26T00:00:00Z
      pageStart:1
      pageEnd:9
      sameAs:https://doi.org/10.1007/s11883-021-00907-6
      keywords:
         Phospholipid transfer protein
         Very low-density lipoprotein production
         High-density lipoprotein metabolism
         Atherosclerosis
         Metabolic syndrome
         Angiology
         Cardiology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11883-021-00907-6/MediaObjects/11883_2021_907_Fig1_HTML.png
      isPartOf:
         name:Current Atherosclerosis Reports
         issn:
            1534-6242
            1523-3804
         volumeNumber:23
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Xian-Cheng Jiang
            affiliation:
                  name:SUNY Downstate Health Sciences University
                  address:
                     name:Department of Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Yang Yu
            affiliation:
                  name:Shandong First Medical University & Shandong Academy of Medical Sciences
                  address:
                     name:Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Current Atherosclerosis Reports
      issn:
         1534-6242
         1523-3804
      volumeNumber:23
Organization:
      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:SUNY Downstate Health Sciences University
      address:
         name:Department of Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, USA
         type:PostalAddress
      name:Shandong First Medical University & Shandong Academy of Medical Sciences
      address:
         name:Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Xian-Cheng Jiang
      affiliation:
            name:SUNY Downstate Health Sciences University
            address:
               name:Department of Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Yang Yu
      affiliation:
            name:Shandong First Medical University & Shandong Academy of Medical Sciences
            address:
               name:Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, USA
      name:Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(417)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

4.46s.