
DOI . ORG {
}
Title[redir]:
The Evolution of Fluorescence-Guided Surgery | Molecular Imaging and Biology
Description:
There has been continual development of fluorescent agents, imaging systems, and their applications over the past several decades. With the recent FDA approvals of 5-aminolevulinic acid, hexaminolevulinate, and pafolacianine, much of the potential that fluorescence offers for image-guided oncologic surgery is now being actualized. In this article, we review the evolution of fluorescence-guided surgery, highlight the milestones which have contributed to successful clinical translation, and examine the future of targeted fluorescence imaging.
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Keywords {🔍}
imaging, pubmed, article, fluorescence, google, scholar, surgery, cancer, tumor, cas, icg, tissue, fluorescent, central, intraoperative, clinical, fluorescenceguided, signal, agents, indocyanine, vivo, surgical, system, green, agent, review, light, fig, angiography, fgs, fluorescein, fda, resection, systems, spy, approval, nir, med, full, van, development, oncologic, targeted, tumors, margins, ala, blue, perfusion, size, lymph,
Topics {✒️}
68 ga-nota-bbn-ir-800cw γ-glutamyltranspeptidase-activated fluorescent probe open-field fluorescence-guided surgery tumor-agnostic ph-activatable nanoprobe article download pdf gene expression profiles intraoperative icg-based fluorescence-angiography fluorescence-guided imaging evolves nanometer-sized micelles enter multiple dual-modality agents affect surgical decision-making high-grade gliomas intraoperatively short-wave infrared imaging methylene blue-current knowledge safe laparoscopic cholecystectomy emergency laparoscopic cholecystectomy image-guided oncologic surgery fluorescence-guided cancer surgery egf-based doxorubicin prodrug folate receptor-α targeting full size image improved surgical decision-making improve surgical decision-making indocyanine green-antibody conjugates receptor-targeted fluorescent probes smart-probes lack capabilities muscle-invasive bladder cancer modalities-phase iii studies ph-activatable fluorescence probes intra-operative perfusion mapping van dam rm surgical oncology controlled closed-field environment selective molecular imaging fluorophore remains extracellular conventional nuclear imaging hexaminolevulinate blue-light cystoscopy fda-approved fluorescent dye fluorescent contrast dyes high-grade gliomas fluorescence molecular imaging reflected white-light images fluorescence-guided surgery related subjects display fluorescence images live molecular navigation dual-modality agent intraoperative surgical guidance van der vegt targeted fluorescent dyes
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headline:The Evolution of Fluorescence-Guided Surgery
description:There has been continual development of fluorescent agents, imaging systems, and their applications over the past several decades. With the recent FDA approvals of 5-aminolevulinic acid, hexaminolevulinate, and pafolacianine, much of the potential that fluorescence offers for image-guided oncologic surgery is now being actualized. In this article, we review the evolution of fluorescence-guided surgery, highlight the milestones which have contributed to successful clinical translation, and examine the future of targeted fluorescence imaging.
datePublished:2022-09-19T00:00:00Z
dateModified:2022-09-19T00:00:00Z
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headline:The Evolution of Fluorescence-Guided Surgery
description:There has been continual development of fluorescent agents, imaging systems, and their applications over the past several decades. With the recent FDA approvals of 5-aminolevulinic acid, hexaminolevulinate, and pafolacianine, much of the potential that fluorescence offers for image-guided oncologic surgery is now being actualized. In this article, we review the evolution of fluorescence-guided surgery, highlight the milestones which have contributed to successful clinical translation, and examine the future of targeted fluorescence imaging.
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